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Related Experiment Video

Updated: May 24, 2026

Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility

Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility

Published on: May 30, 2025

Hormonal evaluation in premature ejaculation.

Metin İshak Oztürk¹, Orhan Koca, Murat Tüken

¹Department of Urology, Haydarpasa Numune Training and Research Hospital, Istanbul, Turkey.

Urologia Internationalis

|March 2, 2012

Summary

Hormonal factors, including higher prolactin and free T4 levels, are associated with premature ejaculation (PE) in men. Evaluating hormonal imbalances may aid in managing this common sexual dysfunction.

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Last Updated: May 24, 2026

Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility

Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility

Published on: May 30, 2025

Area of Science:

Endocrinology
Urology
Sexual Medicine

Background:

Premature ejaculation (PE) is a prevalent sexual dysfunction impacting men's and partners' quality of life.
Hormonal imbalances are increasingly recognized as potential contributors to PE.

Purpose of the Study:

To investigate the association between specific hormonal factors and premature ejaculation (PE).

Main Methods:

A comparative study involving 107 male patients diagnosed with PE and 94 healthy male controls.
Serum hormone levels, including prolactin and free T4, were measured and compared between the groups.

Main Results:

Patients with PE exhibited significantly higher mean serum prolactin and free T4 levels compared to controls.
A higher prevalence of abnormal hormonal parameters, particularly hyperprolactinemia, was observed in the PE group.

Conclusions:

Hormonal factors, such as elevated prolactin and free T4, may play a significant role in the pathophysiology of premature ejaculation (PE).
Consideration of hormonal evaluation is recommended during the assessment of men with PE.