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Province-wide adenovirus type 3 outbreak with severe cases in New Brunswick

Gabriel Girouard1, Richard Garceau, Louise Thibault

  • 1Département de microbiologie et des maladies infectieuses, Centre hospitalier universitaire Dr-Georges-L-Dumont, Moncton, Nouveau-Brunswick;

The Canadian Journal of Infectious Diseases & Medical Microbiology = Journal Canadien Des Maladies Infectieuses Et De La Microbiologie Medicale
|March 2, 2012
PubMed

Insights

Adenovirus can cause severe pneumonia, even in healthy individuals. Consider adenovirus as a cause of community-acquired viral pneumonia, particularly if influenza tests are negative.

Area of Science:

  • Virology
  • Infectious Diseases
  • Public Health

Background:

  • Adenoviruses are common viral pathogens.
  • Severe adenovirus infections are rare but can be life-threatening.
  • Epidemic outbreaks of specific adenovirus strains have been documented.

Observation:

  • An adenovirus type 3 epidemic occurred in New Brunswick from fall 2008 to winter 2009.
  • This outbreak led to three severe cases of illness.
  • One fatality was associated with this adenovirus outbreak.

Findings:

  • Adenovirus type 3 was identified as the causative agent during the New Brunswick epidemic.
  • The identified strain led to severe community-acquired viral pneumonia.
  • A significant case fatality rate was observed in severely ill patients.

Implications:

  • Adenovirus should be considered in the differential diagnosis of severe community-acquired viral pneumonia.
  • Testing for adenovirus is crucial, especially when influenza virus tests are negative.
  • Public health surveillance for adenovirus strains is important for managing potential outbreaks.
Keywords:
AdenovirusOutbreakPneumoniaType 3

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