Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Epistaxis01:30

Epistaxis

Epistaxis, or nosebleeds, occurs when small, swollen blood vessels in the nasal mucous membrane rupture. Typically, the anterior septum is the primary site of occurrence.
Etiology
Possible causes of this condition include high blood pressure, trauma, low humidity, upper respiratory tract infections, allergies, foreign bodies, nasal inhalation of corticosteroids or illicit drugs, excessive use of decongestant nasal sprays, facial or nasal surgery, anatomic malformation, tumors, or systemic...
Asthma-I: Introduction01:29

Asthma-I: Introduction

Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features01:24

Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features

Chronic bronchitis is a key phenotype of chronic obstructive pulmonary disease (COPD), characterized by airway-centered inflammation and mucus overproduction. It develops from long-term exposure to harmful particles or gases, most commonly cigarette smoke, which triggers a persistent inflammatory response.Cellular and Structural ChangesInflammation initially affects the large bronchi and later the smaller airways, with infiltration by immune cells, including neutrophils, macrophages, and...
Asthma III: Clinical Manifestations01:13

Asthma III: Clinical Manifestations

Asthma presents with a characteristic pattern of episodic respiratory symptoms that reflect underlying airway inflammation, bronchoconstriction, and mucus hypersecretion. Although severity varies among individuals, certain clinical manifestations are considered hallmarks of the disorder and often guide diagnosis and assessment.Respiratory SymptomsA persistent cough is one of the most common early features of asthma. It is frequently dry and tends to worsen at night or in the early morning,...
Drugs Used in Upper Respiratory Disorders: Overview01:16

Drugs Used in Upper Respiratory Disorders: Overview

Upper respiratory tract disorders, including viral infections and allergic rhinitis, cause significant discomfort and disrupt daily life. Managing these conditions involves a variety of drugs, such as antihistamines, intranasal steroids, decongestants, antitussives, expectorants, and mucolytics. Specific examples of drugs in each category are provided.
Antihistamines (e.g., Benadryl) block histamines from binding. Histamines are chemicals released during an allergic reaction in the body. As a...
Asthma: Pathogenesis and Management01:20

Asthma: Pathogenesis and Management

Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same authorSame journal

Increased Levels of Serum Eosinophil-Derived Neurotoxin in Patients With Chronic Spontaneous Urticaria.

Allergy, asthma & immunology research·2026
Same author

Endotype Classification of Nonsteroidal Anti-Inflammatory Drug-Exacerbated Respiratory Disease According to Chronic Rhinosinusitis Comorbidity.

Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology·2026
Same author

Clinical remission in allergy and clinical immunology practice: State of the art and World Allergy Organization (WAO) call to action.

The World Allergy Organization journal·2026
Same author

Immunological Basis of Chronic Spontaneous Urticaria: Immunoglobulin E and Beyond.

Yonsei medical journal·2026
Same author

What is new on the horizon for the biologics world: New kids of the block - WAO state of art.

The World Allergy Organization journal·2026
Same author

Impact of Chronic Rhinosinusitis on Long-Term Clinical Outcomes in Adults With Asthma.

The journal of allergy and clinical immunology. In practice·2026

Related Experiment Video

Updated: May 24, 2026

Effects of Exposure of Formaldehyde to a Rat Model of Atopic Dermatitis Induced by Neonatal Capsaicin Treatment
06:47

Effects of Exposure of Formaldehyde to a Rat Model of Atopic Dermatitis Induced by Neonatal Capsaicin Treatment

Published on: September 27, 2017

Occupational rhinitis induced by capsaicin.

Young-Hee Nam1, Hyun Jung Jin, Eui-Kyung Hwang

  • 1Department of Allergy and Clinical Immunology, Ajou University School of Medicine, Suwon, Korea.

Allergy, Asthma & Immunology Research
|March 2, 2012
PubMed
Summary
This summary is machine-generated.

Occupational rhinitis (OR) from capsaicin exposure is reported for the first time. A mill worker experienced nasal symptoms due to capsaicin, suggesting a non-immunological cause for this workplace-induced condition.

Keywords:
Occupational rhinitiscapsaicin

More Related Videos

Precision Induction and Distinction of Coughing and Sneezing Reflexes in Mice
09:30

Precision Induction and Distinction of Coughing and Sneezing Reflexes in Mice

Published on: October 3, 2025

Immunofluorescent Labeling in Nasal Mucosa Tissue Sections of Allergic Rhinitis Rats via Multicolor Immunoassay
06:08

Immunofluorescent Labeling in Nasal Mucosa Tissue Sections of Allergic Rhinitis Rats via Multicolor Immunoassay

Published on: September 22, 2023

Related Experiment Videos

Last Updated: May 24, 2026

Effects of Exposure of Formaldehyde to a Rat Model of Atopic Dermatitis Induced by Neonatal Capsaicin Treatment
06:47

Effects of Exposure of Formaldehyde to a Rat Model of Atopic Dermatitis Induced by Neonatal Capsaicin Treatment

Published on: September 27, 2017

Precision Induction and Distinction of Coughing and Sneezing Reflexes in Mice
09:30

Precision Induction and Distinction of Coughing and Sneezing Reflexes in Mice

Published on: October 3, 2025

Immunofluorescent Labeling in Nasal Mucosa Tissue Sections of Allergic Rhinitis Rats via Multicolor Immunoassay
06:08

Immunofluorescent Labeling in Nasal Mucosa Tissue Sections of Allergic Rhinitis Rats via Multicolor Immunoassay

Published on: September 22, 2023

Area of Science:

  • Occupational health
  • Allergology
  • Toxicology

Background:

  • Capsaicin, the active compound in chili peppers, is known to cause respiratory and nasal irritation.
  • Occupational rhinitis (OR) is a common condition, but capsaicin has not been previously identified as a causative agent.
  • Understanding workplace irritants is crucial for preventing occupational diseases.

Purpose of the Study:

  • To report the first case of occupational rhinitis caused by capsaicin exposure.
  • To investigate the mechanism of capsaicin-induced rhinitis in an occupational setting.
  • To highlight the importance of considering non-allergic triggers in occupational rhinitis.

Main Methods:

  • Case study of a female mill worker with symptoms suggestive of occupational rhinitis.
  • Allergen skin prick testing for common inhalant allergens, including capsaicin.
  • Nasal provocation testing with capsaicin and house dust mite allergen.
  • Symptom scoring and nasal eosinophil counts before and after provocation.

Main Results:

  • The patient developed nasal congestion, rhinorrhea, and itching, aggravated by workplace exposure to capsaicin.
  • Skin prick tests for common allergens, including capsaicin, were negative.
  • Nasal provocation with capsaicin led to increased nasal symptoms and eosinophil counts, which resolved within hours.
  • No significant reaction was observed with house dust mite allergen.

Conclusions:

  • This case represents the first documented instance of occupational rhinitis induced by capsaicin.
  • Capsaicin-induced rhinitis in this patient appears to be mediated by a non-immunological mechanism.
  • Further research is warranted to explore non-allergic pathways in capsaicin-related respiratory conditions.