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Establishment and Evaluation of a Risk Prediction Model for Pathological Escalation of Gastric Low-Grade Intraepithelial Neoplasia
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Published on: February 16, 2024

Role of clinical parameters for predicting the cause of upper gastrointestinal bleeding

Attapon Rattanasupar1

  • 1Division of Gastroenterology, Department of Medicine, Hat Yai Hospital, Songkhla, Thailand. a_rattanasupar@windowslive.com

Journal of the Medical Association of Thailand = Chotmaihet Thangphaet
|March 3, 2012
PubMed

Insights

Predicting upper gastrointestinal bleeding (UGIB) causes is crucial for treatment. Signs of liver disease, cirrhosis, and low hematocrit indicate portal hypertension bleeding, while coffee ground vomitus suggests otherwise.

Area of Science:

  • Gastroenterology
  • Internal Medicine
  • Clinical Research

Background:

  • Upper gastrointestinal bleeding (UGIB) is categorized into portal hypertension (PHT) and non-PHT causes.
  • Accurate differentiation is vital for effective empirical treatment strategies.

Purpose of the Study:

  • To identify clinical parameters that can predict the underlying cause of UGIB.
  • To distinguish between PHT and non-PHT bleeding origins.

Main Methods:

  • Retrospective analysis of 146 UGIB patients undergoing endoscopy within 72 hours.
  • Univariate and multivariate analyses were employed to identify predictive factors.

Main Results:

  • Multivariate analysis revealed cirrhosis, signs of chronic liver disease/PHT, and initial hematocrit < 30% as independent predictors of PHT bleeding.
  • Coffee ground vomitus was the sole factor indicating a reduced likelihood of PHT bleeding.

Conclusions:

  • Underlying cirrhosis, signs of chronic liver disease/PHT, and initial hematocrit < 30% are significantly associated with PHT bleeding.
  • Coffee ground vomitus presentation suggests a lower probability of PHT bleeding.
Abstract

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