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Updated: May 24, 2026

Measuring the Mechanical Properties of Living Cells Using Atomic Force Microscopy
Published on: June 27, 2013
3D mechanical measurements with an atomic force microscope on 1D structures
Christian Kallesøe1, Martin B Larsen, Peter Bøggild
1Department of Micro- and Nanotechnology, Technical University of Denmark, Kgs. Lyngby, DK-2800, Denmark. chkl@teknologisk.dk
Abstract:
We have developed a simple method to characterize the mechanical properties of three dimensional nanostructures, such as nanorods standing up from a substrate. With an atomic force microscope the cantilever probe is used to deflect a horizontally aligned nanorod at different positions along the nanorod, using the apex of the cantilever itself rather than the tip normally used for probing surfaces. This enables accurate determination of nanostructures' spring constant. From these measurements, Young's modulus is found on many individual nanorods with different geometrical and material structures in a short time. Based on this method Young's modulus of carbon nanofibers and epitaxial grown III-V nanowires has been determined.
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