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A Wireless, Bidirectional Interface for In Vivo Recording and Stimulation of Neural Activity in Freely Behaving Rats

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Note: A high dynamic range, linear response transimpedance amplifier.

S Eckel¹, A O Sushkov, S K Lamoreaux

¹Yale University, Department of Physics, P.O. Box 208120, New Haven, Connecticut 06520-8120, USA. stephen.eckel@yale.edu

The Review of Scientific Instruments

|March 3, 2012

Summary

This summary is machine-generated.

We developed a high dynamic range transimpedance amplifier using junction-gate field-effect transistors (JFETs) for linear signal amplification. This novel design achieves multiple output gains, enhancing its utility in sensitive electronic measurements.

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Area of Science:

Electronics
Instrumentation
Semiconductor Devices

Background:

Transimpedance amplifiers (TIAs) are crucial for converting current signals to voltage.
Achieving a high dynamic range and linear response simultaneously presents significant design challenges.
Existing TIAs often compromise linearity or dynamic range for specific applications.

Purpose of the Study:

To design and build a transimpedance amplifier with a nine-decade dynamic range and linear response.
To utilize junction-gate field-effect transistors (JFETs) for gain switching.
To demonstrate a multi-stage amplifier with distinct transimpedance gains.

Main Methods:

Employed junction-gate field-effect transistors (JFETs) to switch feedback resistors.
Utilized a low input bias current operational amplifier.
Configured a three-stage amplifier architecture.

Main Results:

Achieved a high dynamic range (nine decades) with a linear output response.
Demonstrated transimpedance gains of approximately 10^9 Ω, 3 × 10^7 Ω, and 10^4 Ω.
Established an overall bandwidth of 100 Hz, determined by the most sensitive range.

Conclusions:

The developed JFET-based TIA effectively provides a wide dynamic range and linear amplification.
The multi-gain output capability enhances versatility for various signal processing tasks.
This design offers a robust solution for applications requiring precise current-to-voltage conversion over a broad signal spectrum.