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Updated: May 24, 2026
Quantitation of Intra-peritoneal Ovarian Cancer Metastasis
Published on: July 18, 2016
Metastatic hepatic actinomycosis masquerading as distant metastases of ovarian cancer
Young Sun Kim1, Bo Yon Lee, Min Hyung Jung
1Department of Obstetrics and Gynecology, Kyung Hee Medical Center, School of Medicine, Kyung Hee University, Seoul, Republic of Korea.
Abstract:
Actinomycosis is a chronic disease characterized by abscess, tissue fibrosis and draining sinuses. Pelvic actinomycosis in women most commonly occurs during ascending infections, which are usually associated with intrauterine devices; however, secondary hepatic actinomycosis, while rare, can also occur. We describe a patient with an unusual case of metastatic hepatic actinomycosis misdiagnosed as distant metastases of ovarian cancer.
Insights
Actinomycosis is a chronic infection causing abscesses and draining sinuses. This case highlights secondary hepatic actinomycosis, often misdiagnosed, emphasizing the need for accurate diagnosis in women with pelvic infections.
Area of Science:
- Gynecology
- Infectious Diseases
- Hepatology
Background:
- Actinomycosis is a chronic bacterial infection known for abscesses, fibrosis, and draining sinuses.
- Pelvic actinomycosis typically arises from ascending infections, frequently linked to intrauterine device use.
- Secondary hepatic actinomycosis is a rare but recognized clinical presentation.
Observation:
- A patient presented with symptoms initially suggestive of advanced ovarian cancer.
- Imaging and clinical presentation led to a misdiagnosis of distant metastases.
- The patient's condition was ultimately diagnosed as secondary hepatic actinomycosis.
Findings:
- The case illustrates a rare instance of metastatic hepatic actinomycosis.
- The diagnosis was challenging due to its mimicry of ovarian cancer metastases.
- Accurate differentiation between actinomycosis and malignancy is crucial for appropriate treatment.
Implications:
- This case underscores the importance of considering actinomycosis in the differential diagnosis of hepatic lesions, especially in women with a history of pelvic issues.
- Improved diagnostic strategies are needed to distinguish actinomycosis from metastatic cancer.
- Timely and accurate diagnosis of hepatic actinomycosis can prevent delayed or incorrect treatment, improving patient outcomes.
