Related Experiment Video

Updated: May 24, 2026

Seeding and Implantation of a Biosynthetic Tissue-engineered Tracheal Graft in a Mouse Model
09:57

Seeding and Implantation of a Biosynthetic Tissue-engineered Tracheal Graft in a Mouse Model

Published on: April 1, 2019

Surgical reconstruction of tracheal stenosis in conjunction with congenital heart defects

Richard D Mainwaring1, Michael Shillingford, Ryan Davies

  • 1Division of Pediatric Cardiac Surgery, Lucile Packard Children's Hospital, Stanford University School of Medicine, Stanford, California 94305, USA. mainwaring@stanford.edu

The Annals of Thoracic Surgery
|March 3, 2012
PubMed

Insights

Surgical reconstruction effectively treats pediatric airway obstruction, often linked to congenital heart defects. This study highlights successful tracheal reconstruction outcomes in children, even with delayed presentations.

Area of Science:

  • Pediatric Surgery
  • Cardiology
  • Respiratory Medicine

Background:

  • Airway obstruction in children often requires surgical reconstruction.
  • Tracheal stenosis frequently coexists with congenital heart defects, complicating management.
  • This study reviews surgical reconstruction for airway obstruction in children with congenital heart defects.

Purpose of the Study:

  • To review surgical experience with airway obstruction and congenital heart defects.
  • To evaluate outcomes of tracheal reconstruction in this patient population.

Main Methods:

  • Retrospective review of 27 pediatric patients (Feb 2003-Aug 2011).
  • Patients included those with isolated tracheal stenosis or stenosis associated with congenital heart defects.
  • Two groups: concurrent repair (n=13) and delayed presentation after heart defect repair (n=8).

Main Results:

  • Median age at surgery was 9 months.
  • Two postoperative deaths occurred in single-ventricle patients.
  • Median follow-up was 4 years for 25 surviving patients; no tracheal reoperations were needed.

Conclusions:

  • Tracheal obstruction commonly occurs with congenital heart defects.
  • A significant portion of patients presented with delayed airway obstruction after cardiac repair.
  • Tracheal reconstructive techniques proved effective for various causes of airway obstruction.
Abstract

More Related Videos

Heterotopic and Orthotopic Tracheal Transplantation in Mice used as Models to Study the Development of Obliterative Airway Disease09:10

Heterotopic and Orthotopic Tracheal Transplantation in Mice used as Models to Study the Development of Obliterative Airway Disease

Published on: January 20, 2010

Tracheotomy: A Method for Transplantation of Stem Cells to the Lung03:45

Tracheotomy: A Method for Transplantation of Stem Cells to the Lung

Published on: February 25, 2007

Related Concept Videos

Trachea01:22

Trachea

The trachea, commonly known as the windpipe, is a vital part of the human respiratory system. It serves as a passageway for air to travel between the larynx and the bronchi, allowing oxygen to reach the lungs. Let's explore its anatomical features, dimensions, layers of the tracheal wall, associated muscles, and the functions of its parts.
Anatomical Features:
Location: About half of the trachea is situated in the neck, anterior to the esophagus, and extends from the larynx (at the level of the...
Tracheostomy: Procedure and Tubes01:28

Tracheostomy: Procedure and Tubes

A tracheostomy is a surgical procedure that creates an artificial opening into the trachea, typically at the second or third cartilaginous ring level. This opening allows the insertion of a tracheostomy tube, which can replace an endotracheal tube, provide mechanical ventilation, bypass an upper airway obstruction, or remove accumulated tracheobronchial secretions.
Tracheostomy tubes can be made of semiflexible plastic (polyurethane or silicone), rigid plastic, or metal, and they come in...
Tracheostomy Decannulation01:21

Tracheostomy Decannulation

Tracheostomy decannulation is a significant milestone in the liberation of mechanically ventilated patients. Despite its importance, there is no universally accepted protocol for this procedure. This demands an evidence-based, individualized approach.
Description of the Procedure
Decannulation refers to the permanent removal of the tracheostomy tube, signaling the resolution of the condition that initially necessitated the tracheostomy. The process requires a well-coordinated interplay between...
Tracheostomy Care I: Pre-procedural Steps01:16

Tracheostomy Care I: Pre-procedural Steps

A tracheostomy is a surgical technique that involves making an incision in the neck to provide access to the trachea. It is frequently used in medical conditions such as airway obstruction and prolonged mechanical ventilation. Effective nursing management is crucial for the long-term success of a tracheostomy.
Required Equipment
The equipment necessary for tracheostomy care includes:
Oxygen Delivering System III: Tracheostomy and T-piece01:23

Oxygen Delivering System III: Tracheostomy and T-piece

Oxygen delivery is critical in clinical care, especially for patients with respiratory disorders or those undergoing surgical procedures. Various systems, such as tracheostomy and the T-piece, deliver oxygen to the lungs, ensuring adequate arterial oxygenation.
Tracheostomy
A tracheostomy is a surgically created opening (stoma) in the anterior part of the trachea. It is used to establish a patient airway, bypass an upper airway obstruction, simplify the removal of secretions, permit long-term...
Tracheostomy Care II: Procedure01:25

Tracheostomy Care II: Procedure

Tracheostomy care is an essential nursing skill that involves cleaning and maintaining a tracheostomy tube to prevent infection and other complications. Here's a step-by-step guide explaining each procedure with its rationale. Note that disposable gloves are to be worn at all times and changed as often as needed to maintain a sterile work environment, and to protect both patient and healthcare worker.
Step 1: Perform hand hygiene, and put on personal protective equipment: gown, gloves, mask and...