Infective endocarditis presenting as ST-elevation myocardial infarction: an angiographic diagnosis
Benjamin Hibbert1, Mustapha Kazmi, John P Veinot
1Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada.
Insights
Infective endocarditis rarely causes ST elevation myocardial infarction due to coronary artery embolization. This case highlights challenges in diagnosing and managing this rare complication of infective endocarditis.
Area of Science:
- Cardiology
- Infectious Diseases
- Vascular Medicine
Background:
- Systemic embolic events are common in infective endocarditis (IE).
- Coronary artery embolism causing ST elevation myocardial infarction (STEMI) is rare.
- Early recognition and management of IE complications are crucial.
Observation:
- A patient presented with septic shock, ventricular fibrillation, and anterior STEMI.
- Diagnostic angiography revealed IE of a native bicuspid aortic valve with a root abscess.
- Left anterior descending artery occlusion was identified.
Findings:
- Histologic examination of the embolectomy specimen confirmed bacterial thrombus in the left anterior descending artery.
- The findings confirmed coronary embolism of vegetations from IE as the cause of STEMI.
- This case underscores the diagnostic and therapeutic challenges.
Implications:
- Coronary embolism should be considered in patients with IE and myocardial infarction.
- Multidisciplinary management is essential for patients with IE and embolic complications.
- Further research is needed to improve diagnostic and treatment strategies for coronary embolism in IE.
Abstract:
While systemic embolic events occur with relative frequency in infective endocarditis (IE), coronary embolization remains an uncommon cause of ST elevation myocardial infarction. Herein we report a case of ventricular fibrillation and anterior ST elevation myocardial infarction occurring in a patient initially presenting with septic shock. Angiography proved diagnostic for IE of a native bicuspid aortic valve complicated by root abscess and left anterior descending artery occlusion. Histologic examination of the embolectomy specimen from the left anterior descending artery confirmed the presence of thrombus and bacteria. The present case highlights difficulties in identifying and managing patients with coronary embolism of vegetations from IE.
Related Concept Videos
Acute Coronary Syndrome I: Introduction
Endocarditis I: Introduction
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations
Myocarditis II: Clinical Features and Diagnostic Tests
Endocarditis II: Clinical Features of Infective Endocarditis
Acute Coronary Syndrome III: Diagnostic Studies

