Biosynthesis of pyrrolopyrimidines
Related Experiment Video
Updated: Dec 24, 2025

Synthesis of pH Dependent Pyrazole, Imidazole, and Isoindolone Dipyrrinone Fluorophores using a Claisen-Schmidt Condensation Approach
Published on: June 10, 2021
Reid M McCarty1, Vahe Bandarian
1Department of Chemistry and Biochemistry, University of Arizona, 1041 E. Lowell St., Tucson, AZ 85721, USA.
Abstract:
Pyrrolopyrimidine containing compounds, also known as 7-deazapurines, are a collection of purine-based metabolites that have been isolated from a variety of biological sources and have diverse functions which range from secondary metabolism to RNA modification. To date, nearly 35 compounds with the common 7-deazapurine core structure have been described. This article will illustrate the structural diversity of these compounds and review the current state of knowledge on the biosynthetic pathways that give rise to them.
Related Concept Videos
Biosynthesis of Nucleic Acids
Amino Acid Biosynthetic Pathways
Biosynthesis of Polysaccharides
Biosynthesis in Bacteria
Basicity of Heterocyclic Aromatic Amines
Five-Membered Heterocyclic Aromatic Compounds: Overview

