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Preeclampsia and depression: a case-control study in Tehran.

Roghieh Kharaghani¹, Mehrnaz Geranmaye, Leila Janani

¹Reproductive Health Department, Shahroud University of Medical Sciences, Shahroud, Iran. r.kharaghani@yahoo.com

Archives of Gynecology and Obstetrics

|March 3, 2012

Summary

Pregnant women with depression face a higher risk of developing preeclampsia. This study highlights the importance of screening for depression in pregnant individuals to improve maternal and infant health outcomes.

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Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants

Published on: June 13, 2021

Area of Science:

Obstetrics and Gynecology
Perinatal Mental Health
Clinical Psychology

Background:

Preeclampsia is a serious pregnancy complication.
Depression during pregnancy is increasingly recognized as a significant concern.

Purpose of the Study:

To investigate the correlation between preeclampsia and depression in pregnant women.
To assess the prevalence of depression among women with and without preeclampsia.

Main Methods:

A case-control study involving 156 preeclampsia cases and 156 controls.
Data collected via questionnaires including the Patient Health Questionnaire (PHQ-9) for depression assessment.
Statistical analysis included t-tests, Chi-squared tests, and multiple regression.

Main Results:

Moderate to severe depression was observed in 31.2% of preeclampsia cases and 24.8% of controls.
Mild depression was associated with a 1.81-fold increased risk of preeclampsia.
Moderate to severe depression correlated with a 2.52-fold increased risk of preeclampsia, even after adjusting for confounding variables.

Conclusions:

A significant association exists between depression and preeclampsia.
Routine screening for depression in pregnant women is recommended.
Educational interventions for mental health during pregnancy are crucial.