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Updated: May 24, 2026
A Murine Model of Fetal Exposure to Maternal Inflammation to Study the Effects of Acute Chorioamnionitis on Newborn Intestinal Development
Published on: June 24, 2020
Chorioretinitis in infants
Monika Modrzejewska1, Ewelina Lachowicz, Danuta Karczewicz
1Chair and Clinic of Ophthalmology, Pomeranian Medical University, Szczecin, Poland. monika_modrzej@op.pl
Purpose:
The aim of this review is to present cases of chorioretinitis in infants caused by viral and parasitic infections.
Material And Methods:
Four infants with viral chorioretinitis were identified in a routine ophthalmological examination. Laboratory tests towards bacterial, viral and parasitic diseases were performed.
Results:
Toxoplasmosis, rubella, and CMV infections were diagnosed in clinical and laboratory tests. After a wide spectrum of therapy a total remission of inflammatory process in all the discussed children was observed.
Conclusions:
Posterior uveitis is an ocular complication which can be connected with viral or parasitic infections in postnatal period. Prematurity, normal delivery, intrauterine transmission, breast feeding, comorbid diseases might be associated with chorioretinitis in infants.
Insights
This review highlights viral and parasitic infections causing chorioretinitis in infants. Prompt diagnosis and treatment led to complete remission of inflammation in all cases.
Area of Science:
- Ophthalmology
- Pediatrics
- Infectious Diseases
Background:
- Chorioretinitis in infants can stem from various infections.
- Early identification is crucial for effective management and visual prognosis.
Purpose of the Study:
- To present cases of infant chorioretinitis caused by viral and parasitic infections.
- To discuss potential risk factors associated with these infections.
Main Methods:
- Case identification of four infants with viral chorioretinitis during routine ophthalmological examinations.
- Comprehensive laboratory testing for bacterial, viral, and parasitic pathogens.
Main Results:
- Diagnoses included toxoplasmosis, rubella, and cytomegalovirus (CMV) infections.
- All infants achieved complete remission of the inflammatory process following broad-spectrum therapy.
Conclusions:
- Posterior uveitis in infants can be linked to postnatal viral or parasitic infections.
- Factors such as prematurity, delivery method, intrauterine transmission, breastfeeding, and comorbidities may be associated with infant chorioretinitis.
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