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Related Concept Videos

Skin Diseases and Disorders01:23

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
The JAK-STAT Signaling Pathway01:20

The JAK-STAT Signaling Pathway

Several cytokine receptors have tightly bound Janus kinase or JAK proteins attached at their cytosolic tail. Small signaling molecules such as cytokines, growth hormones, or prolactins bind to the cytokine receptors and initiate their dimerization. The dimerization brings the cytosolic JAKs together that trans-phosphorylate and activates each other. The activated JAKs now phosphorylate cytosolic tails of the cytokine receptors, which serve as binding sites for adaptor proteins such as  SH2...
Atherosclerosis III: Management01:26

Atherosclerosis III: Management

Management of atherosclerosis involves an integrated strategy encompassing pharmacological treatment, surgical interventions, lifestyle changes, and nutrition therapy to address the multifactorial nature of the disease.Pharmacological TherapyA cornerstone of atherosclerosis management is the use of pharmacological agents. Statins, such as atorvastatin, are pivotal in inhibiting HMG-CoA reductase, an enzyme that catalyzes an initial step in cholesterol synthesis in the liver. This reduction in...
T Cell Types and Functions01:24

T Cell Types and Functions

When T cells with CD4 markers are activated, they give rise to two types of effector cells: helper T cells and regulatory T cells. Meanwhile, T cells with CD8 markers differentiate into effector cytotoxic T cells. The differentiation of CD4 T cells into helper T cell subsets, such as Th1, Th2, and Th17 cells, is dependent on the antigen type, antigen-presenting cell, and regulatory cytokines.
Th1 cells stimulate dendritic cells to express necessary co-stimulatory molecules on their surfaces for...
Peripheral Artery Disease I: Introduction01:30

Peripheral Artery Disease I: Introduction

Peripheral artery disease (PAD) predominantly results from atherosclerosis, which involves the accumulation of fatty deposits, or plaques, within the walls of arteries. This causes them to narrow and harden, significantly reducing blood flow. PAD predominantly affects the legs, particularly the arteries supplying the thighs and calves. In rare cases, it may involve other arteries, including those in the arms.Etiology of PAD:The principal cause of PAD is atherosclerosis, which results from fatty...
Role of Skin in Vitamin D Synthesis01:23

Role of Skin in Vitamin D Synthesis

The skin plays a crucial role in the synthesis of vitamin D, a vital nutrient for various physiological processes in the body. Vitamin D is unique because it can be synthesized in the skin through a series of chemical reactions triggered by exposure to ultraviolet B (UVB) radiation from sunlight.
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin D3(cholecalciferol).

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Related Experiment Video

Updated: May 24, 2026

Measuring Psoriasis Severity at Home
02:28

Measuring Psoriasis Severity at Home

Published on: March 1, 2024

Psoriasis and physical activity: a review.

P B Wilson1, K A Bohjanen, S J Ingraham

  • 1School of Kinesiology, University of Minnesota, Minneapolis, MN, USA. wilso733@umn.edu

Journal of the European Academy of Dermatology and Venereology : JEADV
|March 6, 2012
PubMed
Summary
This summary is machine-generated.

Physical activity may help manage psoriasis and its related health issues like heart disease and diabetes. More research is needed to confirm the benefits of exercise for psoriasis patients.

Related Experiment Videos

Last Updated: May 24, 2026

Measuring Psoriasis Severity at Home
02:28

Measuring Psoriasis Severity at Home

Published on: March 1, 2024

Area of Science:

  • Dermatology
  • Cardiology
  • Endocrinology

Background:

  • Psoriasis is a chronic inflammatory skin condition impacting quality of life.
  • Individuals with moderate-to-severe psoriasis face higher risks of cardiometabolic diseases.
  • Physical activity is a known treatment for cardiometabolic conditions but understudied in psoriasis.

Purpose of the Study:

  • To review the limited research on physical activity in psoriasis.
  • To explore shared physiological pathways between physical activity, psoriasis, and cardiometabolic comorbidities.
  • To highlight the need for future research on physical activity interventions for psoriasis.

Main Methods:

  • Literature review of existing studies on physical activity and psoriasis.
  • Analysis of physiological links between adiposity, inflammation, oxidative stress, lipids, and psoriasis.
  • Examination of potential epigenetic influences of physical activity.

Main Results:

  • Shared physiological pathways link physical activity, psoriasis, and cardiometabolic risks.
  • Increased adiposity, inflammation, oxidative stress, and lipid levels are implicated.
  • Physical and psychosocial impairments in psoriasis may hinder activity participation.

Conclusions:

  • Physical activity may be a beneficial intervention for psoriasis management.
  • Further studies are needed to establish the efficacy of physical activity interventions in improving functioning and reducing comorbidities in psoriasis patients.
  • Understanding the interplay between physical activity, psoriasis, and cardiometabolic health is crucial.