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A Reversible, Non-invasive Method for Airway Resistance Measurements and Bronchoalveolar Lavage Fluid Sampling in Mice
Published on: April 13, 2010
[The development of remission in patients with bronchial asthma]
Abstract:
The efficacy of the therapeutic programs and rehabilitation measures for achievement of a permanent remission of bronchial asthma was studied in 436 patients, 18 to 71 years of age (mean age 45.3 years), 283 women and 153 men. In 42.89% of the patients the asthma was severe, in 47.07% it was moderate and in 10.09%--mild. 30.05% of the patients were with atopic asthma, 52.06%--with infectious dependence, 8.03%--with glucocorticoid deficiency and 2.98%--with hormonal imbalance. In all patients remission was achieved with a different reliability. Full remission was achieved in 24.08%, partial remission 1 degree--in 58.03% and partial remission II degree--in 17.89% of the patients. The duration of the remission varied from 2 up to 46 months. A remission longer than 6 months was achieved in 72.10% of the patients treated with intal or zaditen, in 61.36% of the patients treated with corticosteroids and only in 27.70% of the patients treated with symptomatic and general hygienic means. The duration and the quality of the remission depend on the correct selection of the therapy in the acute stage, the severity and the form of bronchial asthma. Better results are achieved in the mild form of bronchial asthma. The most frequent causes for destabilization of the remission were bronchopulmonary infections, incorrect reduction or discontinuing of the medication, formal supportive therapy, psychologic demobilization and irrational supportive therapy.
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