Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Development of Immunocompetence

Development of Immunocompetence

The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Structure-informed deep generation enables de novo metabolite annotation in untargeted metabolomics.

Nature communications·2026

Same author

Synergistic Effects of Liquid Solute Concentration and Cooling Rate on Secondary α<sub>2</sub>-Al Formation in High-Solid-Fraction Rheo-Diecast Al-Si Alloys: An Integrated Experimental and Phase-Field Study.

Materials (Basel, Switzerland)·2026

Same author

Phosvitin-Derived Peptide Pt5-1c Is a Pro-Angiogenic Agent Capable of Enhancing Wound Healing.

Biomolecules·2026

Same author

GNPNAT1 acts as a prognostic biomarker associated with immune infiltration in lung adenocarcinoma and promotes the proliferation and invasion of cancer cells.

Discover oncology·2025

Same author

Donkey Milk Improves Dextran Sulfate Sodium-Induced Ulcerative Colitis by Protecting Gut Barrier Function, Inhibiting the TLR4/MyD88/NF-κB Signaling Pathway, and Modulating Gut Microbiota.

Food science & nutrition·2025

Same author

Effects of Cooling Rate and Solid Fraction on α-Al Phase Evolution in Rheo-Die Casting: Phase-Field Simulation and Experimental Investigation.

Materials (Basel, Switzerland)·2025

Same journal

Widespread macrophage expression of FcRY enables IgY recycling in avian species.

Developmental and comparative immunology·2026

Same journal

Screening of proteins interacting with the bacterial-origin horizontal transferred serine/threonine-protein kinase in Pacific white shrimp Litopenaeus vannamei.

Developmental and comparative immunology·2026

Same journal

Scallop Toll-like Receptor Engages in Complex Interactions with Diverse MyD88 Proteins and Orchestrates Host Innate Immune Responses.

Developmental and comparative immunology·2026

Same journal

Genome-wide identification and characterization of β-defensin genes across sixteen Eulipotyphla species: Insights into gene diversification and evolutionary dynamics.

Developmental and comparative immunology·2026

Same journal

Characterization of interleukin-20 from black carp and its role in the antiviral innate immunity.

Developmental and comparative immunology·2026

Same journal

The spatiotemporal immune response patterns of Gryllus bimaculatus to infection by the bioinsecticide Metarhizium anisopliae.

Developmental and comparative immunology·2026

See all related articles

Search research articles

Related Experiment Video

Updated: May 24, 2026

Immunization of Adult Zebrafish for the Preclinical Screening of DNA-based Vaccines

Immunization of Adult Zebrafish for the Preclinical Screening of DNA-based Vaccines

Published on: October 30, 2018

Maternal immunity in fish.

Shicui Zhang¹, Zhiping Wang, Hongmiao Wang

¹Institute of Evolution and Marine Biodiversity and Department of Marine Biology, Ocean University of China, Qingdao 266003, China. sczhang@ouc.edu.cn

Developmental and Comparative Immunology

|March 6, 2012

Summary

This summary is machine-generated.

Maternal transfer of immune factors like antibodies and yolk proteins enhances fish larvae defense against pathogens. Understanding these mechanisms is crucial for improving fish survival rates.

More Related Videos

Non-invasive Imaging of the Innate Immune Response in a Zebrafish Larval Model of Streptococcus iniae Infection

Non-invasive Imaging of the Innate Immune Response in a Zebrafish Larval Model of Streptococcus iniae Infection

Published on: April 21, 2015

Quantification of the Respiratory Burst Response as an Indicator of Innate Immune Health in Zebrafish

Quantification of the Respiratory Burst Response as an Indicator of Innate Immune Health in Zebrafish

Published on: September 12, 2013

Related Experiment Videos

Last Updated: May 24, 2026

Immunization of Adult Zebrafish for the Preclinical Screening of DNA-based Vaccines

Immunization of Adult Zebrafish for the Preclinical Screening of DNA-based Vaccines

Published on: October 30, 2018

Non-invasive Imaging of the Innate Immune Response in a Zebrafish Larval Model of Streptococcus iniae Infection

Non-invasive Imaging of the Innate Immune Response in a Zebrafish Larval Model of Streptococcus iniae Infection

Published on: April 21, 2015

Quantification of the Respiratory Burst Response as an Indicator of Innate Immune Health in Zebrafish

Quantification of the Respiratory Burst Response as an Indicator of Innate Immune Health in Zebrafish

Published on: September 12, 2013

Area of Science:

* Immunology
* Aquaculture
* Fish Biology

Background:

* Maternal transfer of innate and adaptive immune factors (IgM, lysozymes, lectin, cathelicidin, complement) occurs in fish.
* Yolk proteins (phosvitin, lipovitellin) also serve as maternally-transferred immune factors for teleost larvae.
* Mechanisms of transfer and action for most factors remain largely unknown.

Purpose of the Study:

* To review the known maternally-transferred immune factors in fish.
* To highlight the gaps in understanding transfer mechanisms and modes of action.
* To discuss factors influencing maternal immunity transfer and its practical applications.

Main Methods:

* Literature review of existing studies on maternal immune transfer in fish.
* Synthesis of information on various immune factors and their roles.
* Analysis of factors affecting maternal immunity and potential manipulation strategies.

Main Results:

* Identified key immune factors transferred from mother to offspring in fish.
* Highlighted that the functions of most maternally-transferred factors are not fully understood.
* Noted that transfer mechanisms are largely unknown, with some exceptions for IgM and yolk proteins.
* Biological and environmental factors significantly impact maternal immunity transfer.

Conclusions:

* Maternal immune transfer is vital for fish offspring defense against pathogens.
* Further research is needed to elucidate the mechanisms and functions of these factors.
* Manipulating maternal immunity offers a promising strategy for enhancing fish larval survival in aquaculture.