[Edema caused by isolated hyperthermic perfusion of the extremities]

Isolated extremity perfusion today is an undisputed alternative to amputation and a causal form of therapy for locally and regionally metastasising melanomas. In order to avoid the most serious complications such treatment should only be carried out at special centres. Milder side-effects such as early and late postoperative oedema respond well to drug regimes and manual lymphatic drainage.