Multiple coronary artery thrombosis in a 41-year-old male patient presenting with ST-segment elevation myocardial

Jassim Al Suwaidi1, Awad Al-Qahtani

  • 1Department of Cardiology and Cardiovascular Surgery, Hamad General Hospital, P.O. Box 3050, Doha, Qatar. Jha01@hmc.org.qa

Insights

Simultaneous occlusion of the right coronary artery and left anterior descending artery is rare in ST-segment elevation myocardial infarction (STEMI). Prompt percutaneous coronary intervention (PCI) is crucial for survival in these complex STEMI cases.

Area of Science:

  • Cardiology
  • Interventional Cardiology

Background:

  • ST-segment elevation myocardial infarction (STEMI) typically involves single epicardial coronary artery occlusion.
  • Simultaneous multi-vessel occlusion is an infrequent yet critical presentation.

Observation:

  • A 41-year-old male presented with inferior and anterior STEMI.
  • The patient experienced cardiogenic shock and life-threatening ventricular arrhythmias.
  • Acute occlusion of both the proximal right coronary artery (RCA) and proximal left anterior descending (LAD) coronary arteries was diagnosed.

Findings:

  • Primary percutaneous coronary interventions (PCI) were successfully performed on both the occluded RCA and LAD.
  • Intra-aortic balloon pump (IABP) placement demonstrated significant clinical improvement.

Implications:

  • This case highlights the importance of early diagnosis and intervention in rare multi-vessel STEMI.
  • Prompt PCI for simultaneous proximal RCA and LAD occlusion is critical for patient survival.
  • Aggressive management including revascularization and hemodynamic support is essential.

Related Concept Videos

Acute Coronary Syndrome I: Introduction01:30

Acute Coronary Syndrome I: Introduction

Acute Coronary Syndrome (ACS) encompasses a spectrum of heart conditions caused by sudden obstruction of coronary arteries, typically resulting from the rupture of an atherosclerotic plaque and subsequent thrombus (blood clot) formation. This obstruction can lead to partial or complete blockage of blood flow, causing varying degrees of myocardial ischemia or infarction.ACS includes the following clinical entities:Unstable Angina (UA)Non-ST-Elevation Myocardial Infarction (NSTEMI)ST-Elevation...
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations01:19

Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations

The pathophysiology of Acute Coronary Syndrome [ACD] involves several key processes:The main underlying cause of ACD is atherosclerosis, a chronic inflammatory disease characterized by the buildup of lipid-laden plaques within the coronary arteries.As the atherosclerotic plaque grows in the coronary artery, it may become unstable due to the formation of a lipid-rich core and a thin fibrous cap. Inflammatory cells within the plaque, such as macrophages, secrete enzymes that degrade the...
Acute Coronary Syndrome III: Diagnostic Studies01:30

Acute Coronary Syndrome III: Diagnostic Studies

Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
Coronary Artery Disease III: Clinical Manifestations01:30

Coronary Artery Disease III: Clinical Manifestations

Coronary Artery Disease (CAD) is a primary health risk worldwide, leading to significant morbidity and mortality. The condition arises from the buildup of atherosclerotic plaques within the coronary arteries, resulting in diminished blood supply to the heart muscle.The clinical manifestations of CAD vary widely, from asymptomatic stages to severe, life-threatening conditions. Understanding these manifestations is crucial for early diagnosis and effective management.Angina Pectoris: The Warning...
Acute Coronary Syndrome IV: Interprofessional Care01:28

Acute Coronary Syndrome IV: Interprofessional Care

IntroductionThe management of Acute Coronary Syndrome (ACS) aims to minimize myocardial damage, preserve myocardial function, and prevent complications.Initial ManagementInpatient management involves continuous cardiac monitoring, preferably in an ICU, focusing on blood pressure, serum sodium, potassium, and creatinine levels, and urine output. Ongoing pharmacologic management is crucial for stabilizing the patient.Supplemental Oxygen: Administer supplemental oxygen if oxygen saturation is...
Coronary Artery Disease II: Pathophysiology01:26

Coronary Artery Disease II: Pathophysiology

Coronary Artery Disease (CAD) originates from a series of events that impair the function of coronary arteries, the blood vessels responsible for delivering oxygen-rich blood to the heart muscle. The pathophysiology of CAD is closely linked to atherosclerosis, a chronic inflammatory and lipid-driven condition affecting the vascular endothelium.1. Endothelial DamageThe process begins with damage to the vascular endothelium, which serves as a protective barrier between the blood and the vessel...