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Updated: Jul 20, 2026

An Experimental Paradigm for the Prediction of Post-Operative Pain (PPOP)
Published on: January 27, 2010
A pilot study of pain management during rehabilitation for hip and knee arthroplasty
J Mukand1, C Cai, C Fitzsimmons
1Southern New England Rehabilitation Center, Providence, RI 02907, USA.
Unlabelled:
{\it
Objective:
} To evaluate the efficacy of pain management in a clinical pathway for rehabilitation after hip and knee arthroplasty, in which scheduled medications are rapidly tapered and prn medications are continued throughout the inpatient stay. {\it
Study Design:
} A prospective cross-sectional study. {\it
Setting:
} General rehabilitation unit of a regional acute rehabilitation center. {\it
Patients:
} Twenty-nine patients admitted consecutively to the rehabilitation unit in three months. {\it
Outcome Measures:
} Number of pills/day of prn pain medication, pain scores at admission and discharge, frequency of constipation and nausea, Functional Independence Measure (FIM) gain, and length of stay (LOS). {\it
Results:
} For all patients, prn pain medication use was 2.4 pills/day/patient; the mean FIM gain was 22.1; and the average LOS was 9.8 days. In comparison to the Vicodin group, patients on Darvocet N-100 had significantly fewer requests for prn pain medication each day (3.1 vs. 1.1, p < 0.01), significantly better FIM gains better (18.9 vs. 24.1, p < 0.05), and fewer side effects (nausea and constipation). {\it
Conclusion:
} Choosing the right pain medication is imperative for achieving optimal efficiency in clinical pathways for orthopedic rehabilitation. In this pilot study, Darvocet N-100 is the preferred narcotic over codeine and its derivatives.
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