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Updated: May 24, 2026

Enzymatic Cascade Reactions for the Synthesis of Chiral Amino Alcohols from L-lysine
Published on: February 16, 2018
Aminohydroxyacetone synthons: versatile intermediates for the organocatalytic asymmetric aldol reaction
Yoshiyuki Komatsu1, Riki Watanabe, Hideaki Ikishima
1Laboratory of Natural Products Chemistry, Faculty of Science, Kochi University, Kochi 780-8520, Japan.
Abstract:
A practical method for the synthesis of 1,3-aminohydroxyacetone synthons was developed, and their utility in the organocatalytic asymmetric aldol reaction was demonstrated in a short synthesis of aza-sugars.
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