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Related Concept Videos

Cardiomyopathy V: Interprofessional Care01:29

Cardiomyopathy V: Interprofessional Care

Managing cardiomyopathy involves addressing underlying or precipitating causes, treating heart failure with medications, and implementing dietary changes and a balanced exercise and rest regimen.Lifestyle ModificationsCardiomyopathy patients should adopt a low-sodium diet to reduce fluid retention and manage heart failure. A personalized exercise and rest plan helps maintain physical fitness without overstraining the heart. Avoiding alcohol and tobacco is essential to prevent further damage to...
Cardiomyopathy II: Dilated Cardiomyopathy01:30

Cardiomyopathy II: Dilated Cardiomyopathy

Dilated cardiomyopathy, or DCM, is a progressive myocardial disorder characterized by ventricular chamber dilation and contractile dysfunction.EtiologyVarious factors can cause DCM, including hypertension and heavy alcohol intake, which contribute to the weakening and enlargement of the heart muscle. Viral infections, such as Coxsackievirus B, adenoviruses, and influenza, can lead to DCM by causing inflammation and damage to heart tissue. Certain chemotherapeutic agents, including daunorubicin,...
Dysrhythmias VI: Management of Dysrhythmias01:25

Dysrhythmias VI: Management of Dysrhythmias

Dysrhythmia management involves a multifaceted approach, incorporating pharmacological treatments, medical procedures, surgical interventions, lifestyle modifications, and patient education.Pharmacological ManagementAntiarrhythmic Drugs:Class I (Sodium Channel Blockers): This class includes quinidine and procainamide, which reduce the speed of impulse conduction in the heart, stabilize the cardiac membrane, and control arrhythmias. Quinidine and procainamide are Class IA agents that prolong the...
Cardiomyopathy III: Hypertrophic Cardiomyopathy01:29

Cardiomyopathy III: Hypertrophic Cardiomyopathy

Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
Disturbances in Heart Rhythm01:29

Disturbances in Heart Rhythm

Arrhythmia or dysrhythmia refers to an abnormal heart rhythm caused by a defect in the heart's conduction system. It can cause the heart to beat irregularly, too quickly, or too slowly, leading to symptoms like chest pain, shortness of breath, and fainting. Factors such as stress, caffeine, alcohol, nicotine, cocaine, certain drugs, congenital defects, diseases, and electrolyte abnormalities can trigger arrhythmias.
Arrhythmias are categorized by their speed, rhythm, and origin. A slow heart...
Cardiopulmonary Resuscitation III: AED Use01:23

Cardiopulmonary Resuscitation III: AED Use

Introduction to AEDAn Automated External Defibrillator (AED) is a portable medical device that analyzes the heart's rhythm and, if necessary, delivers an electrical shock to help the heart re-establish an effective rhythm during sudden cardiac arrest (SCA). SCA occurs when the heart suddenly and unexpectedly stops beating, leading to a loss of blood flow to the brain and other vital organs. In such emergencies, time is of the essence, and using an AED, combined with Cardiopulmonary...

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Related Experiment Video

Updated: May 24, 2026

A New Single Chamber Implantable Defibrillator with Atrial Sensing: A Practical Demonstration of Sensing and Ease of Implantation
16:40

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Published on: February 28, 2012

Implantable cardioverter defibrillator harm?

Maurizio Gasparini1, Seah Nisam

  • 1IRCCS Istituto Clinico Humanitas, Via Manzoni 56, 20089 Rozzano-Milano, Italy. maurizio.gasparini@humanitas.it

Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology
|March 6, 2012
PubMed
Summary

Implantable cardioverter defibrillators (ICDs) and CRT-Ds offer net benefits despite concerns about shocks. Advances in technology and practice minimize harm, improving patient prognosis and quality of life.

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Implantation of Total Artificial Heart in Congenital Heart Disease
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Implantation of Total Artificial Heart in Congenital Heart Disease

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Last Updated: May 24, 2026

A New Single Chamber Implantable Defibrillator with Atrial Sensing: A Practical Demonstration of Sensing and Ease of Implantation
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Published on: February 28, 2012

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Area of Science:

  • Cardiology
  • Medical Devices
  • Electrophysiology

Background:

  • Implantable cardioverter defibrillators (ICDs) and cardiac resynchronization therapy defibrillators (CRT-Ds) are widely accepted treatments.
  • Recent concerns have arisen regarding potential harm from ICDs, specifically concerning quality of life and adverse effects of shocks.

Purpose of the Study:

  • To evaluate the overall benefit versus harm of ICD/CRT-D therapy.
  • To assess the impact of ICD/CRT-D therapy on prognosis, shock effects, and quality of life.
  • To highlight technological and practice advancements in minimizing ICD complications.

Main Methods:

  • Review of evidence from multiple ICD/CRT-D trials.
  • Analysis of patient outcomes considering both benefits and complications.
  • Examination of advancements in device technology and physician practices.

Main Results:

  • Multiple trials indicate that patients receive a net benefit from ICD/CRT-D therapy, outweighing potential harm.
  • Therapy positively impacts prognosis, shock management, and quality of life.
  • Technological and practice improvements focus on minimizing shocks, favoring antitachycardia pacing and incorporating cardiac resynchronization pacing for heart failure management.

Conclusions:

  • Despite acknowledged complications, ICD/CRT-D therapy provides substantial protection for appropriately selected patients.
  • Ongoing advancements in technology and clinical practice continue to enhance the safety and efficacy of these devices.
  • The evidence strongly supports the net benefit of ICD/CRT-D therapy in improving patient outcomes.