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Published on: February 8, 2019
Pericarditis revealing large vessel vasculitis
Bruno Couturier1, Valerie Huyge, Muhammad S Soyfoo
1Department of Internal Medicine, Erasme Hospital, Université Libre de Bruxelles, 1070 Bruxelles, Belgium.
Insights
Giant cell arteritis, a form of large vessel vasculitis, typically presents with inflammation and headaches. This case highlights how Fluorodeoxyglucose-Positron Emission Tomography (FDG-PET) can reveal large vessel vasculitis in patients initially presenting with pericarditis.
Area of Science:
- Cardiology
- Rheumatology
- Nuclear Medicine
Background:
- Large vessel vasculitis (LVV), including Giant Cell Arteritis (GCA), is an inflammatory condition affecting major arteries.
- GCA diagnosis traditionally relies on temporal artery biopsy, which can be invasive and may yield false negatives.
Observation:
- A patient presented with symptoms mimicking pericarditis, a condition affecting the heart's outer lining.
- Initial diagnostic workup did not immediately suggest underlying vasculitis.
Findings:
- Fluorodeoxyglucose-Positron Emission Tomography (FDG-PET) imaging identified characteristic signs of large vessel vasculitis.
- This imaging modality proved crucial in uncovering the underlying vasculitic process.
Implications:
- FDG-PET may serve as a valuable non-invasive tool for diagnosing LVV, especially in atypical presentations.
- Early and accurate diagnosis of LVV can lead to timely intervention and improved patient outcomes.
Abstract:
Large vessels vasculitis and more specifically, Giant cell arteritis, is characterized by increased inflammatory markers, headaches and altered clinical status. Diagnosis is confirmed by biopsy of temporal arteries showing the presence of granuloma and vasculitis. We hereby report the case of a patient presenting initially as pericarditis and revealing large vessel vasculitis using FDG-PET.
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