Related Experiment Video
Updated: May 24, 2026

08:53
Randomized, Triple-Blind, and Parallel-Controlled Trial of Transcranial Direct Current Stimulation for Cognitive Rehabilitation after Stroke
Published on: June 6, 2025
Pilot randomized controlled trial investigating cognitive strategy use to improve goal performance after stroke
Summary
The Cognitive Orientation to daily Occupational Performance (CO-OP) intervention led to greater improvements in post-stroke client performance compared to standard occupational therapy. Further research with larger samples is recommended.
Area of Science:
- Neurorehabilitation
- Occupational Therapy
Background:
- Stroke survivors often experience significant challenges in daily occupational performance.
- Standard occupational therapy (SOT) provides task-specific and component-based training.
- The Cognitive Orientation to daily Occupational Performance (CO-OP) is a client-centered cognitive strategy approach.
Purpose of the Study:
- To compare the effectiveness of the CO-OP intervention versus SOT on post-stroke goal performance.
- To determine the magnitude and direction of changes in occupational performance after stroke.
Main Methods:
- A randomized trial involving eight community-dwelling stroke survivors.
- Participants were assigned to either CO-OP (n=4) or SOT (n=4).
- Goal performance was assessed using the Performance Quality Rating Scale (PQRS) and Canadian Occupational Performance Measure (COPM).
Main Results:
- CO-OP participants showed significantly greater improvements in performance (PQRS, p=.02; COPM Performance, p=.02) compared to SOT.
- No significant difference was found in participant satisfaction (COPM Satisfaction, p=.38).
Conclusions:
- The CO-OP intervention demonstrated superior performance improvements in stroke survivors compared to SOT.
- The findings suggest CO-OP as a promising approach for post-stroke rehabilitation.
- Larger sample studies are warranted to confirm these results.

