Related Experiment Videos
Hb level in relation to vitamin D status in healthy infants and toddlers
Khalid K Abdul-Razzak1, Abeer M Khoursheed, Shoroq M Altawalbeh
1Department of Clinical Pharmacy, Faculty of Pharmacy, Jordan University of Science and Technology, PO Box 3030, Irbid-22110, Jordan. kkalani@just.edu.jo
Insights
Vitamin D deficiency is common in Jordanian infants and toddlers, but this study found no link between low vitamin D levels and anemia. Further research is needed to understand anemia causes in this population.
Area of Science:
- Pediatric Nutrition
- Hematology
- Public Health
Background:
- Vitamin D deficiency and anemia are prevalent in Jordanian infants and toddlers.
- Understanding the relationship between these conditions is crucial for child health.
Purpose of the Study:
- To investigate the association between vitamin D deficiency and anemia in Jordanian infants and toddlers.
- To determine if vitamin D deficiency is a risk factor for anemia in this age group.
Main Methods:
- A cross-sectional prospective study was conducted.
- 203 healthy infants and children aged 6-36 months were recruited from a primary care setting in Jordan.
Main Results:
- The overall prevalence of anemia was 40.4%.
- Anemia was more common in infants (51.8%) than toddlers (26.9%).
- No significant association was found between vitamin D status and anemia.
Conclusions:
- Vitamin D deficiency does not appear to be a risk factor for anemia in Jordanian infants and toddlers.
- The high prevalence of anemia warrants further investigation into other contributing factors.
Objective:
To assess the presence of an association between vitamin D deficiency and anaemia in Jordanian infants and toddlers, in whom both vitamin D deficiency and anaemia have previously been proved to be common separately.
Design:
Cross-sectional prospective study.
Setting:
Department of Paediatrics, Princess Rahma Teaching Hospital, Jordan.
Subjects:
Healthy infants and children aged 6-36 months who were seen for primary care.
Results:
Out of 203 infants and toddlers included in the study, the anaemia prevalence was 40·4 %. The prevalence of anaemia among infants (n 110) was 51·8 %, whereas it was 26·9 % among toddlers (n 93). No association between vitamin D status and anaemia was found.
Conclusions:
Vitamin D deficiency is not a risk for anaemia in infants and toddlers.
Related Concept Videos
Role of Skin in Vitamin D Synthesis
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin D3(cholecalciferol).
Role of Vitamins in Maintaining Bone Health
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption
Vitamins
Development of Immunocompetence
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
Drug Dosing: Infants and Children