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Published on: October 12, 2017
Urinary iodine and sodium status of urban Korean subjects: a pilot study
Jonghyeon Choi1, Hyo-Sik Kim, Duck Jin Hong
1Department of Laboratory Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea.
Objectives:
We estimated iodine status of Korean population by determining the concentration of spot urinary iodine (UI) with a reliable method based on the Sandell-Kolthoff reaction.
Materials And Methods:
A total of 540 urine samples from apparently healthy subjects were collected, and UI, urinary sodium (UNa), and urinary creatinine (UCr) were determined from those samples and analyzed with age.
Results:
There were significant decreases in either UI (P<0.0001), UI/UCr ratio (P=0.0001), UNa (P<0.0001), or UNa/Cr ratio (P=0.0001) in younger subjects than older ones. The median value of UI was 267.6 μg/L, but the median UI of the younger group (191.8 μg/L) was significantly decreased compared to that of the older group (383.9 μg/L).
Conclusions:
This study showed that the median of UI in Korean urban population was in a more than adequate iodine nutritional state, but UI was significantly different between the younger age group and the older age group.
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