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Related Concept Videos

Drug Toxicity: Risk factors01:24

Drug Toxicity: Risk factors

Adverse Drug Reactions (ADRs) are potential complications that arise during pharmacotherapy, influenced by multiple risk factors. Age plays a significant role; both neonates and the elderly are at heightened risk due to their respective immature and diminished metabolic and elimination processes. Gender also impacts ADRs, with females experiencing a 1.5 to 1.7-fold greater risk than males, which may be linked to pharmacokinetic, pharmacodynamic, and hormonal differences. Notably, neonates, the...
Factors Affecting Illness01:18

Factors Affecting Illness

When a person's physical, emotional, intellectual, social development or spiritual functioning is compromised, this deviation from a healthy normal state is called illness. Illness creates stress that in turn harms individuals. Irritation, anger, denial, hopelessness, and fear are behavioral and emotional changes an individual experiences in the phases of illness. A variety of factors influence a person's health and well-being.
For instance, risk factors are connected to illness, disability,...
Factors Affecting the Risk of Infection01:26

Factors Affecting the Risk of Infection

The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin create...
Pharmacodynamics in Geriatric Patients: Effects of Age01:27

Pharmacodynamics in Geriatric Patients: Effects of Age

Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...
Alzheimer Disease l: Introduction01:29

Alzheimer Disease l: Introduction

Alzheimer disease is a chronic, progressive, and irreversible neurodegenerative disorder and the most common cause of dementia in older adults. It leads to gradual neuronal loss, causing cognitive decline, behavioral changes, and loss of functional independence.Risk Factors and EtiologyThe disease is multifactorial. Age is the strongest risk factor, with prevalence doubling every 5 years after age 65. Genetic factors include mutations in genes such as APP, PSEN1, and PSEN2, which are associated...
Cancer Prevention02:59

Cancer Prevention

Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...

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Related Experiment Video

Updated: May 24, 2026

A Phenotyping Regimen for Genetically Modified Mice Used to Study Genes Implicated in Human Diseases of Aging
09:37

A Phenotyping Regimen for Genetically Modified Mice Used to Study Genes Implicated in Human Diseases of Aging

Published on: July 14, 2016

Age as a risk factor.

Ravi Dhingra1, Ramachandran S Vasan

  • 1Section of Cardiology, Dartmouth Medical School, Heart and Vascular Center, Dartmouth-Hitchcock Medical Center, Lebanon, NH 03756, USA.

The Medical Clinics of North America
|March 7, 2012
PubMed
Summary

This review examines how age impacts cardiovascular disease (CVD) risk prediction. It explores age as a modifiable factor and its influence on cardiac and vascular health.

Area of Science:

  • Cardiology
  • Preventive Medicine
  • Gerontology

Background:

  • Cardiovascular disease (CVD) risk is primarily assessed using traditional risk factors.
  • Age is a well-established, yet often considered nonmodifiable, traditional risk factor for CVD.
  • Understanding age's role is crucial for accurate CVD risk stratification.

Purpose of the Study:

  • To review the utilization of individual age in CVD incidence prediction models.
  • To explore the potential modifiability of age as a CVD risk factor.
  • To discuss methods for evaluating short-term and long-term CVD risk and communicating it effectively.

Main Methods:

  • Literature review of studies on age and CVD risk.
  • Analysis of various CVD risk scoring systems incorporating age.

Related Experiment Videos

Last Updated: May 24, 2026

A Phenotyping Regimen for Genetically Modified Mice Used to Study Genes Implicated in Human Diseases of Aging
09:37

A Phenotyping Regimen for Genetically Modified Mice Used to Study Genes Implicated in Human Diseases of Aging

Published on: July 14, 2016

  • Examination of research on age-related modifications of cardiovascular risk factors.

    • Main Results:

    • Age is a significant predictor in most CVD risk scores.
    • The concept of age as a modifiable risk factor is complex and requires further investigation.
    • Age influences multiple cardiac and vascular risk factors, affecting overall CVD risk.

    Conclusions:

    • Accurate communication of age-related CVD risk is essential for patient management.
    • Further research is needed to explore interventions that may modify age-related CVD risk.
    • Integrating age-specific data enhances the precision of CVD risk assessment.