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A case of infantile star anise toxicity
Gregory Russell Madden1, Kristine Held Schmitz, Katherine Fullerton
1University of Virginia School of Medicine, Charlottesville, VA 22903, USA. grm7q@virginia.edu
Insights
Japanese star anise (Illicium anisatum) ingestion caused toxicity in an infant, mimicking colic symptoms. Prompt recognition and management are crucial for infant safety and preventing adverse outcomes.
Area of Science:
- Toxicology
- Pediatrics
- Herbal Medicine
Background:
- Chinese star anise (Illicium verum) is commonly used for infantile colic.
- Japanese star anise (Illicium anisatum) contamination is linked to infant toxicity.
Observation:
- A 3-month-old infant presented with toxicity symptoms after star anise ingestion.
- Clinical presentation included gastrointestinal and neurological findings consistent with toxicity.
Findings:
- The infant's symptoms were attributed to accidental ingestion of toxic Japanese star anise.
- Differential diagnosis included other causes of infant distress and neurological symptoms.
Implications:
- Highlights the risk of toxic plant contamination in herbal remedies for infants.
- Emphasizes the need for accurate identification of herbal products and prompt medical evaluation.
- Informs clinical management strategies for suspected star anise toxicity in infants.
Abstract:
Chinese star anise (Illicium verum) is a popular herbal remedy for infantile colic. Contamination with a related species of Japanese star anise (Illicium anisatum) has been related to cases of toxicity in infants. We report the case of a 3-month-old infant girl who presented to the emergency department with signs and symptoms of toxicity after recent star anise ingestion. Her presentation is consistent with other reports of toxicity that include particular gastrointestinal and neurological findings. A discussion of the clinical aspects of star anise toxicity, differential diagnosis, and management follows.
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