Optimizing surgical approach for natural orifice translumenal endoscopic procedures
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Updated: May 24, 2026

Lateral Molar Approach-Driven Transoral Endoscopic Procedure for Benign Infratemporal Fossa Tumor Resection
Published on: August 15, 2025
Maria A Cassera1, Bin Zheng, Georg O Spaun
1Gastrointestinal and Minimally Invasive Surgery Division, The Oregon Clinic, 1040 NW 22nd Ave, Suite 560, Portland, OR 97210, USA. mcassera@orclinic.com
Background:
Natural orifice translumenal endoscopic surgery (NOTES) often requires some degree of retroflexion of the endoscopic operating system. This study investigates the impact of retroflexion on task performance in NOTES.
Methods:
In a bench-top simulation, surgeons were required to manipulate a single-channel endoscope to touch 4 dots in a predetermined order. The task was performed under the forward-view and retroflexed-view conditions.
Results:
Tasks performed under the forward-view condition were significantly faster than those performed under the retroflexed-view condition (P = .005). Also, 5 experienced surgeons completed tasks in less time than the novices (P = .043). Experienced surgeons were mildly affected by the inverted image, whereas the novices were vulnerable to image malalignment.
Conclusion:
Careful selection of the surgical approach to avoid image malalignment is suggested for safe performance of NOTES. Extensive training is required for novices to overcome the vision-motion difficulty before they can perform NOTES safely and effectively.
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