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Prevalence of cleft lip and palate in western Slovakia in the years 2001-2007

J Fedeles1, P Ziak, M Krizko

  • 1Department of Hand Surgery, Comenius University Hospital, Bratislava, Slovakia. fedelesmd@gmail.com

Bratislavske Lekarske Listy
|March 8, 2012
PubMed

Insights

The prevalence of orofacial clefts (OC) in Western Slovakia decreased from 1985-2000 to 2001-2007, with a higher incidence observed in the Bratislava region. This study analyzed 220 children with OC to understand epidemiological trends.

Area of Science:

  • Medical Science
  • Epidemiology
  • Public Health

Background:

  • Orofacial clefts (OC) are common congenital anomalies with significant public health implications.
  • Understanding the epidemiological trends and geographical variations of OC is crucial for targeted interventions.

Purpose of the Study:

  • To investigate the prevalence of orofacial clefts (OC) in live newborns in Western Slovakia between 2001 and 2007.
  • To correlate OC occurrence with seasonal and geographical factors, and analyze epidemiological trends.
  • To compare OC prevalence between the Bratislava region and other Western Slovakia regions.

Main Methods:

  • Retrospective active survey collecting clinical data of 220 children with OC treated at a cleft center in Bratislava.
  • Data included patients from Bratislava region (n=67) and other Western Slovakia regions (n=151).
  • Live birth data were obtained from the Health Statistics of the Slovak Republic.

Main Results:

  • Total incidence of OC in Western Slovakia (2001-2007) was 1.49/1000 live births, a decrease from 1.64/1000 live births (1985-2000).
  • Bratislava region showed a higher prevalence (1.82/1000 live births) compared to other Western Slovakia regions (1.37/1000 live births).
  • The most frequent cleft types were cleft palate (CP) at 38.6%, followed by cleft lip and palate (CLP) at 35.5%, and cleft lip (CL) at 24.1%.

Conclusions:

  • The overall risk rate for OC in Western Slovakia was 1 in 671 live births.
  • A higher prevalence of OC was confirmed in the Bratislava region (1 in 549 live births) compared to the rest of Western Slovakia (1 in 730 live births).
  • The findings indicate a decreasing trend in OC prevalence but highlight regional disparities within Western Slovakia.
Abstract

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