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Short communication: adhesion pathways utilized by HIV-infected lymphocytes

Yu-hua Chow1, Li Liu, Barbara Schwartz

  • 1Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Washington, Seattle, WA, USA.

AIDS Research and Human Retroviruses
|March 8, 2012
PubMed
Summary

Human immunodeficiency virus (HIV)-infected lymphocytes utilize cyclin-dependent kinase 4 (Cdk4) for adhesion to endothelial matrix and fibronectin. Rap-1 activity is also required for adhesion in these cells, suggesting new therapeutic targets.

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