Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Assessment of long-term changes in airway function.

N B Pride1

  • 1Department of Medicine, Royal Postgraduate Medical School, London, United Kingdom.

Agents and Actions. Supplements
|January 1, 1990
PubMed
Summary

Long-term tracking of reduced forced expiratory volume in one second (FEV1) in middle-aged male smokers can predict disability and death. Individual FEV1 decline rates stabilize over time, but differences persist among smokers.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Relation between trunk fat volume and reduction of total lung capacity in obese men.

Journal of applied physiology (Bethesda, Md. : 1985)·2011
Same author

Reduction of total lung capacity in obese men: comparison of total intrathoracic and gas volumes.

Journal of applied physiology (Bethesda, Md. : 1985)·2010
Same author

Possible protection by inhaled budesonide against ischaemic cardiac events in mild COPD.

The European respiratory journal·2007
Same author

Predictors of COPD symptoms: does the sex of the patient matter?

The European respiratory journal·2006
Same author

Projections of COPD in males in The Netherlands.

The European respiratory journal·2006
Same author

Ageing and changes in lung mechanics.

The European respiratory journal·2005

Area of Science:

  • Pulmonary Medicine
  • Respiratory Health
  • Clinical Epidemiology

Background:

  • Forced expiratory volume in one second (FEV1) decline is a key indicator in smokers.
  • Predictive value of FEV1 tracking for long-term outcomes is established in some populations.
  • Variability in FEV1 decline among smokers with similar histories necessitates further investigation.

Purpose of the Study:

  • To evaluate the long-term prognostic value of FEV1 decline in middle-aged male smokers.
  • To assess the stability of individual FEV1 decline rates over time.
  • To explore the utility of post-bronchodilator FEV1 and other lung function tests.

Main Methods:

  • Longitudinal tracking of FEV1 measurements in a cohort of middle-aged male smokers.
  • Analysis of the distribution and stabilization of individual FEV1 decline rates.
  • Comparison of prognostic information from FEV1 with other respiratory tests.

Main Results:

  • Evidence supports long-term tracking of FEV1 decline predicting disability and death in this group.
  • Individual FEV1 decline rates stabilize after 4-5 years of follow-up.
  • Significant unexplained differences in FEV1 decline exist between individuals with similar smoking histories.

Conclusions:

  • Monitoring FEV1 decline is valuable for predicting long-term outcomes in middle-aged male smokers.
  • While FEV1 decline rates stabilize, individual variability remains a significant factor.
  • The prognostic value of post-bronchodilator FEV1 and other advanced lung function tests requires further research.

Related Experiment Videos