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Gamma knife radiosurgery for jugular foramen schwannomas
Selçuk Peker1, Meriç Sengöz, Türker Kılıç
1Department of Neurosurgery, Acıbadem University School of Medicine, Istanbul, Turkey. peker@selcukpeker.com
Abstract:
Jugular foramen schwannomas are very rare tumors. Advances in skull base surgery have led to more aggressive resection of these tumors, but surgery may associate with development of new neurological deficits. In this report, we analyze the long-term results for 17 patients with newly diagnosed or residual/recurrent jugular foramen schwannoma who underwent gamma-knife treatment. During a mean 64 months of follow-up, magnetic resonance imaging revealed reduced tumor size in 13 cases and no size change in four cases. The tumor growth control rate was 100% and only one patient had transient hoarseness. For patients who have small- to moderate-sized jugular foramen schwannomas, gamma-knife radiosurgery is associated with good tumor control and carries minimal risk of adverse radiation effects.
Insights
Gamma-knife radiosurgery offers excellent tumor control for jugular foramen schwannomas. This treatment is safe and effective for small to moderate-sized tumors, with minimal adverse effects observed in long-term follow-up.
Area of Science:
- Neurosurgery
- Radiation Oncology
- Oncology
Background:
- Jugular foramen schwannomas are rare tumors.
- Surgical resection can lead to new neurological deficits.
- Gamma-knife radiosurgery presents an alternative treatment option.
Purpose of the Study:
- To analyze the long-term results of gamma-knife treatment for jugular foramen schwannomas.
- To evaluate tumor control and adverse effects.
- To assess the efficacy of radiosurgery for newly diagnosed or residual/recurrent tumors.
Main Methods:
- Retrospective analysis of 17 patients with jugular foramen schwannoma.
- Treatment with gamma-knife radiosurgery.
- Long-term follow-up with magnetic resonance imaging (MRI) for a mean of 64 months.
Main Results:
- 100% tumor growth control rate observed.
- Tumor size reduction in 13 patients; no change in four.
- Only one patient experienced transient hoarseness, indicating minimal adverse effects.
Conclusions:
- Gamma-knife radiosurgery is associated with good tumor control for small- to moderate-sized jugular foramen schwannomas.
- The treatment carries a minimal risk of adverse radiation effects.
- Radiosurgery is a viable and safe option for managing these rare tumors.
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