Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Heart Failure VI: Adjunct Therapies

Heart Failure VI: Adjunct Therapies

Additional therapies for treating patients with heart failure (HF) may include procedural interventions, supplemental oxygen, the management of sleep disorders, and nutritional therapy.Procedural InterventionsImplantable Cardioverter-Defibrillator: For patients at risk of life-threatening arrhythmias due to severe left ventricular dysfunction, an Implantable Cardioverter-Defibrillator (ICD) can detect and terminate these arrhythmias, preventing sudden cardiac death and improving survival rates.

Cardiomyopathy V: Interprofessional Care

Cardiomyopathy V: Interprofessional Care

Managing cardiomyopathy involves addressing underlying or precipitating causes, treating heart failure with medications, and implementing dietary changes and a balanced exercise and rest regimen.Lifestyle ModificationsCardiomyopathy patients should adopt a low-sodium diet to reduce fluid retention and manage heart failure. A personalized exercise and rest plan helps maintain physical fitness without overstraining the heart. Avoiding alcohol and tobacco is essential to prevent further damage to...

Cardiomyopathy II: Dilated Cardiomyopathy

Cardiomyopathy II: Dilated Cardiomyopathy

Dilated cardiomyopathy, or DCM, is a progressive myocardial disorder characterized by ventricular chamber dilation and contractile dysfunction.EtiologyVarious factors can cause DCM, including hypertension and heavy alcohol intake, which contribute to the weakening and enlargement of the heart muscle. Viral infections, such as Coxsackievirus B, adenoviruses, and influenza, can lead to DCM by causing inflammation and damage to heart tissue. Certain chemotherapeutic agents, including daunorubicin,...

Cardiomyopathy VII: Pre and Post Operative Nursing Management

Cardiomyopathy VII: Pre and Post Operative Nursing Management

Patients with hypertrophic cardiomyopathy (HCM) and left ventricular outflow tract (LVOT) obstruction who remain symptomatic despite optimal medical therapy may undergo a septal myectomy (Morrow procedure). This procedure involves excising a portion of the hypertrophied septum below the aortic valve using a heart-lung machine to improve blood flow through the LVOT. Effective preoperative and postoperative nursing management ensures successful patient outcomes, minimizes complications, and...

Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications

Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications

Peritoneal dialysis (PD) is a medical process that removes waste products and excess fluid from the body using the peritoneal membrane as a natural filter.Peritoneal Dialysis MethodsSeveral methods can be used for peritoneal dialysis, including Acute Intermittent Peritoneal Dialysis, Continuous Ambulatory Peritoneal Dialysis, and Automated Peritoneal Dialysis, also known as Continuous Cyclic Peritoneal Dialysis.Acute Intermittent Peritoneal Dialysis (AIPD) is used for patients with uremic...

Peripheral Artery Disease V: Postoperative Nursing Management

Peripheral Artery Disease V: Postoperative Nursing Management

During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Resection of Intrapericardial Lymphangioma Invasive to Ventricular Apex via Left Anterolateral Thoracotomy.

Annals of thoracic surgery short reports·2026

Same author

A retrospective pilot crossover study of protocolized transition from inhaled nitric oxide to inhaled epoprostenol in adult cardiothoracic surgery.

JHLT open·2026

Same author

Acute HeartMate3 Malfunction Requiring Exchange Due to Intrapump Obstruction: Inflow Cannula Obstruction Can Cause HM3 Failure.

ASAIO journal (American Society for Artificial Internal Organs : 1992)·2026

Same author

Listing patterns at the highest volume heart transplant centers: Multiple roads to transplant.

JHLT open·2026

Same author

Impact of left ventricular assist device implantation on right ventricular-pulmonary arterial coupling assessed by high-fidelity hemodynamics.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation·2025

Same author

Impact of HeartMate 3 left ventricular assist device infection on outcomes following heart transplant.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation·2025

Search research articles

Related Experiment Video

Updated: May 24, 2026

Utilizing Percutaneous Ventricular Assist Devices in Acute Myocardial Infarction Complicated by Cardiogenic Shock

Utilizing Percutaneous Ventricular Assist Devices in Acute Myocardial Infarction Complicated by Cardiogenic Shock

Published on: June 12, 2021

Mechanical circulatory support: devices, outcomes and complications.

Carmelo A Milano¹, Alan A Simeone

¹Department of Cardiothoracic Surgery, Duke University, Durham, NC 27710, USA. carmelo.milano@duke.edu

Heart Failure Reviews

|March 8, 2012

Summary

Advanced heart failure remains a global challenge despite medical and device advancements. This review focuses on implantable mechanical circulatory support devices as evolving options for end-stage heart failure patients.

More Related Videos

Use of a Percutaneous Ventricular Assist Device/Left Atrium to Femoral Artery Bypass System for Cardiogenic Shock

Use of a Percutaneous Ventricular Assist Device/Left Atrium to Femoral Artery Bypass System for Cardiogenic Shock

Published on: August 16, 2021

Related Experiment Videos

Last Updated: May 24, 2026

Utilizing Percutaneous Ventricular Assist Devices in Acute Myocardial Infarction Complicated by Cardiogenic Shock

Utilizing Percutaneous Ventricular Assist Devices in Acute Myocardial Infarction Complicated by Cardiogenic Shock

Published on: June 12, 2021

Use of a Percutaneous Ventricular Assist Device/Left Atrium to Femoral Artery Bypass System for Cardiogenic Shock

Use of a Percutaneous Ventricular Assist Device/Left Atrium to Femoral Artery Bypass System for Cardiogenic Shock

Published on: August 16, 2021

Area of Science:

Cardiology
Biomedical Engineering

Background:

Systolic heart failure (SHF) is a significant global health issue.
Medical management (beta-blockers, RAAS modulation, diuretics) and devices (CRT, ICDs) have improved outcomes, but many patients progress to end-stage disease.
Heart transplantation is effective but limited by donor availability and recipient criteria.

Purpose of the Study:

To review the milestones and current state of implantable mechanical circulatory support devices for advanced heart failure.
To emphasize evolving technologies in device development for intermediate to long-term circulatory support.

Main Methods:

Literature review of historical and recent advancements in mechanical circulatory support devices.
Focus on implantable technologies for advanced heart failure treatment.

Main Results:

Significant progress in medical and device therapies for heart failure over 25 years.
Despite progress, many patients experience progressive dysfunction, limiting activity and leading to adverse outcomes.
Mechanical circulatory support devices have evolved significantly, offering new therapeutic options.

Conclusions:

Implantable mechanical circulatory support devices represent a critical advancement in managing end-stage heart failure.
Technological evolution has broadened treatment options beyond transplantation.
These devices offer hope for improved outcomes and quality of life for patients with advanced heart failure.