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09:25
Establishment of Cancer Stem Cell Cultures from Human Conventional Osteosarcoma
Published on: October 14, 2016
Primary osteosarcoma of the ureter
Zhuo Zhang1, Hongyan Li, Haiyan Zhang
1Urology Surgery Department, Sino-Japanese Friendship Hospital (The Third Clinical Hospital), Norman Bethune College of Medicine, Jilin University, Changchun 130033, People's Republic of China.
The American Journal of the Medical Sciences
|March 8, 2012
Summary
This report details an extremely rare case of primary osteosarcoma of the ureter in a 64-year-old woman. Successful surgical removal and pathological findings confirmed high-grade extraosseous osteosarcoma.
Area of Science:
- Oncology
- Uropathology
- Surgical Pathology
Background:
- Primary osteosarcoma of the ureter is exceptionally rare.
- This condition requires accurate diagnosis and effective management.
Observation:
- A 64-year-old woman presented with a papillary mass obstructing the ureter.
- Ureteroscopy revealed the tumor occluding the ureteral lumen.
Findings:
- Pathologic analysis confirmed high-grade extraosseous osteosarcoma with mitotically active spindle cells and osteoid.
- Immunohistochemistry showed vimentin positivity and negativity for cytokeratins (CK, CK7, CK20) and leukocyte-common antigen.
- The patient experienced a good surgical outcome with no recurrence at 6 months.
Implications:
- This case adds to the limited literature on primary ureteral osteosarcoma.
- Highlights the importance of considering rare malignancies in urologic diagnosis.
- Successful surgical resection offers a favorable prognosis for this rare tumor.
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