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Related Concept Videos

Myocarditis I: Introduction01:21

Myocarditis I: Introduction

Myocarditis is inflammation of the myocardium, which is the muscular layer of the heart.EtiologyMyocarditis has a diverse etiology, including a wide range of infectious and non-infectious causes:Infectious CausesViral: Common viruses include Coxsackie A and B, adenovirus, parvovirus B19, enteroviruses, and influenza A.Bacterial: Examples include infections caused by Streptococcus, Staphylococcus, and Mycoplasma species.Rickettsial: Infections like Rocky Mountain spotted fever can result in...
Ischemic Heart Disease: Overview01:17

Ischemic Heart Disease: Overview

Ischemic heart disease occurs when the heart's blood supply dwindles, causing an ominous lack of oxygen and nutrients. This deficiency, stemming from reduced or obstructed blood flow, spells danger, leading to heart muscle damage and dysfunction.
Atherosclerosis, the primary malefactor, orchestrates this dangerous condition. It manifests as the accumulation of fatty deposits, akin to insidious plaques, within arterial walls. As time elapses, these plaques metamorphose, hardening and narrowing...
Acute Coronary Syndrome I: Introduction01:30

Acute Coronary Syndrome I: Introduction

Acute Coronary Syndrome (ACS) encompasses a spectrum of heart conditions caused by sudden obstruction of coronary arteries, typically resulting from the rupture of an atherosclerotic plaque and subsequent thrombus (blood clot) formation. This obstruction can lead to partial or complete blockage of blood flow, causing varying degrees of myocardial ischemia or infarction.ACS includes the following clinical entities:Unstable Angina (UA)Non-ST-Elevation Myocardial Infarction (NSTEMI)ST-Elevation...
Imbalances in Cardiac Output01:26

Imbalances in Cardiac Output

The heart's primary function is to pump blood throughout the body, maintaining a balance between blood sent out (cardiac output) and blood returning (venous return). If this balance is disrupted, it can result in congestive heart failure (CHF), a severe condition where the heart becomes an inefficient pump, leading to inadequate blood circulation.
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to send blood...
Cardiomyopathy III: Hypertrophic Cardiomyopathy01:29

Cardiomyopathy III: Hypertrophic Cardiomyopathy

Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
Myocarditis III: Medical Management01:14

Myocarditis III: Medical Management

Myocarditis: Comprehensive Medical ManagementMyocarditis, the heart muscle inflammation, requires a comprehensive medical management strategy that addresses the underlying cause, provides supportive care, manages symptoms, and reduces cardiac workload.Infections and Autoimmune CausesAdminister appropriate antimicrobial therapy when an infectious agent causes myocarditis. For instance, penicillin treats infections caused by Group A Streptococcus. In cases where autoimmune processes are...

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Related Experiment Video

Updated: May 24, 2026

Minimal Invasive Surgical Procedure of Inducing Myocardial Infarction in Mice
09:05

Minimal Invasive Surgical Procedure of Inducing Myocardial Infarction in Mice

Published on: May 4, 2015

Myocardial infarction in the elderly.

Amelia Carro1, Juan Carlos Kaski

  • 1Cardiovascular Sciences Research Centre, Division of Clinical Sciences, St George's University of London, London, United Kingdom.

Aging and Disease
|March 8, 2012
PubMed
Summary
This summary is machine-generated.

Elderly patients with acute myocardial infarction (AMI) often receive less evidence-based treatment than younger patients. This review examines current recommendations for managing AMI in older individuals, considering their unique challenges.

Keywords:
Management of elderly patientsacute myocardial infarctionagemyocardial reperfusion

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Post-Myocardial Infarction Heart Failure in Closed-chest Coronary Occlusion/Reperfusion Model in Göttingen Minipigs and Landrace Pigs

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Last Updated: May 24, 2026

Minimal Invasive Surgical Procedure of Inducing Myocardial Infarction in Mice
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Published on: May 4, 2015

Myocardial Infarction and Functional Outcome Assessment in Pigs
12:03

Myocardial Infarction and Functional Outcome Assessment in Pigs

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Post-Myocardial Infarction Heart Failure in Closed-chest Coronary Occlusion/Reperfusion Model in Göttingen Minipigs and Landrace Pigs
14:35

Post-Myocardial Infarction Heart Failure in Closed-chest Coronary Occlusion/Reperfusion Model in Göttingen Minipigs and Landrace Pigs

Published on: April 17, 2021

Area of Science:

  • Cardiology
  • Geriatric Medicine
  • Clinical Practice Guidelines

Background:

  • Acute myocardial infarction (AMI) outcomes have improved with modern treatments.
  • Elderly AMI patients may receive less evidence-based care compared to younger populations.
  • Underlying reasons include treatment benefit uncertainty and increased comorbidity risks in older adults.

Purpose of the Study:

  • To review current management recommendations for acute myocardial infarction (AMI) in elderly patients.
  • To address the complexities in diagnosing and managing AMI in older individuals.
  • To highlight challenges in applying trial data to the geriatric population.

Main Methods:

  • Review of current clinical practice guidelines for AMI management.
  • Analysis of factors influencing treatment decisions in elderly patients.
  • Synthesis of evidence pertaining to geriatric considerations in acute coronary syndromes.

Main Results:

  • Elderly patients present unique challenges in AMI diagnosis and treatment.
  • Comorbidities, functional status, and polypharmacy complicate care for older adults.
  • Evidence-based treatments may be underutilized in this demographic due to perceived risks and trial exclusions.

Conclusions:

  • Management of AMI in the elderly requires tailored approaches.
  • Addressing comorbidities and individual patient factors is crucial for optimal outcomes.
  • Further research is needed to clarify treatment benefits and risks in older AMI patients.