Phenylpropanolamine hydrochloride

Phenylpropanolamine has been classified by the FDA advisory review panel as generally safe and effective for short-term weight control. The maximum daily dose for this indication is 75 mg. When used in recommended doses by patients without significant risk factors, serious side effects appear to occur infrequently. The pharmacist has an important role in preventing misuse and abuse of phenylpropanolamine through counseling the patient about its appropriate, short-term (not exceeding 12 weeks) use in a comprehensive weight-reduction program. Patients should be alerted to signs and symptoms of serious adverse reactions and advised to discontinue use if any reactions appear.