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Updated: May 24, 2026

Electrophoretic Delivery of γ-aminobutyric Acid (GABA) into Epileptic Focus Prevents Seizures in Mice
Published on: May 16, 2019
Dilemma of antiepileptic drugs withdrawal in symptomatic epilepsy
Dubravka Sepić Grahovac1, Goran Bajek, Dinko Vitezić
1University of Rijeka, School of Medicine, Rijeka, Croatia. poliklinika.interneuron@ri.t-com.hr
Abstract:
A successful treatment of epilepsy depends on numerous factors such as etiology, genetics and environmental impact. An exact diagnosis, treatment and an adequate selection of antiepileptic drugs (AED) are important from the very beginning. The patient with symptomatic epilepsy caused by the brain tumor (low-grade astrocytoma in the left parietal lobe, surgically removed 17 years after the first manifestation of illness) is presented in this study. He has been seizure free for 6 years. The represented case study deals with the risk-benefit analysis of the discontinuation of the prescribed antiepileptic treatment that has lasted for 23 years.
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