Left ventricular noncompaction: clinical-echocardiographic study

Aleksandra Nikolić1, Ljiljana Jovović, Slobodan Tomić

  • 1Faculty of Medicine, University of Belgrade, Belgrade, Serbia. nikolicdrsasa@gmail.com

Insights

Left ventricular noncompaction (LVNC) is a rare heart muscle disorder. This study found 12 cases in 3,854 outpatients, suggesting a potentially higher prevalence than previously thought.

Area of Science:

  • Cardiology
  • Cardiovascular Diseases
  • Medical Diagnostics

Background:

  • Left ventricular noncompaction (LVNC) is a rare endomyocardial morphogenesis disorder.
  • It can occur in isolation or with congenital heart disease and neuromuscular diseases.
  • LVNC is linked to high mortality, heart failure, arrhythmias, and thromboembolic events.

Purpose of the Study:

  • To determine the prevalence of LVNC in outpatients.
  • To analyze the clinical presentation of LVNC.
  • To utilize clinical and echocardiographic findings for diagnosis.

Main Methods:

  • A study of 3,854 consecutive outpatients from January 2006 to January 2007.
  • Echocardiographic examinations were performed using Vivid 7 GE Medical System equipment.
  • Analysis of echocardiographic parameters and clinical presentation in patients meeting LVNC criteria.

Main Results:

  • Twelve out of 3,854 patients (0.31%) met the echocardiographic criteria for LVNC.
  • The mean age at diagnosis was 45 years (±15 years), with 7 males.
  • Seven patients showed signs of heart failure; six experienced arrhythmias, with no embolic events.

Conclusions:

  • The prevalence of LVNC may be underestimated in the general population.
  • Further research is needed to fully understand and address LVNC.
  • Early recognition and diagnosis are crucial due to significant morbidity and mortality.
Abstract

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