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Published on: February 14, 2011
Immunomodulatory effects of antimicrobial agents. Part II: antiparasitic and antifungal agents
1Inserm SC14 Centre d'Expertise Collective, Université Paris Diderot Paris, 7 Faculté de Médecine Site Bichat, 16 rue Henri Huchard, 75890, Paris Cedex 18, France. marie-therese.labro@inserm.fr
Abstract:
Antiparasitic and antifungal drugs have not received the same high level of recognition as antimicrobial drugs. They are comparatively few in number, the great majority of them were developed more than a century ago, they have many adverse side effects and are subject to the emergence of drug resistance. The second part of the review, devoted to the immunomodulatory effects of antimicrobial agents, addresses the interference of antiparasitic and antifungal agents with the host natural defenses and the deleterious or beneficial consequences of these properties.
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