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Updated: May 24, 2026
05:42
An Ex Vivo Model of Ovarian Cancer Peritoneal Metastasis Using Human Omentum
Published on: January 26, 2024
Peritoneal tuberculosis mimicking ovarian cancer
Tufan Oge1, S Sinan Ozalp, Omer T Yalcin
1Eskisehir Osmangazi University School of Medicine, Eskisehir, Turkey. tufanoge@yahoo.com
Summary
Tuberculous peritonitis (TBP) can mimic ovarian cancer, leading to misdiagnosis. Ultrasound-guided biopsy and frozen section analysis are crucial for accurate diagnosis and avoiding unnecessary radical surgery.
Area of Science:
- Gynecologic Oncology
- Infectious Diseases
- Abdominal Imaging
Background:
- Tuberculous peritonitis (TBP) is an uncommon form of abdominal tuberculosis.
- TBP can present with symptoms and imaging findings similar to ovarian cancer, posing diagnostic challenges.
Purpose of the Study:
- To evaluate the clinical characteristics of patients with tuberculous peritonitis (TBP) misdiagnosed as ovarian cancer.
- To assess diagnostic methods and surgical outcomes in these cases.
Main Methods:
- Retrospective review of 20 patients diagnosed with TBP mimicking ovarian cancer between 2000-2011.
- Analysis of demographic data, clinical presentation, laboratory results (including CA 125), imaging (ultrasound, CT), and surgical/pathological findings.
Main Results:
- The mean age was 37.5 years; common symptoms included abdominal pain and distension.
- Elevated CA 125 levels (mean 289 IU/ml) were noted in 80% of patients.
- Imaging revealed ascites (85%) and pelvic masses (60%). Diagnostic laparotomy, laparoscopy, and ultrasound-guided tru-cut biopsy were performed. Surgical findings included miliary nodules, adhesions, and adnexal masses.
Conclusions:
- Preoperative differentiation between TBP and ovarian cancer is challenging.
- Laparotomy is often necessary for definitive diagnosis.
- Ultrasound-guided tru-cut biopsy and frozen section analysis can aid in diagnosis and prevent unnecessary radical surgery.
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