Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
Pulmonary Tuberculosis II01:28

Pulmonary Tuberculosis II

Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Brain Abscess l: Introduction01:26

Brain Abscess l: Introduction

A brain abscess is a focal, intracerebral infection characterized by a localized collection of pus within the brain parenchyma, resulting from microbial invasion and the body’s inflammatory response. It progresses through stages: early and late cerebritis, followed by early and late capsule formation, reflecting tissue destruction, immune response, and eventual encapsulation.Etiology and PathogenesisCausative organisms vary with source and host factors, often involving polymicrobial infections,...
Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Cranial and Spinal Meninges01:19

Cranial and Spinal Meninges

The cranial and spinal meninges are complex protective structures surrounding the central nervous system (CNS), consisting of the brain and spinal cord. These meninges consist of the dura mater, the arachnoid mater, and the pia mater. They protect the CNS, provide structural support, and aid in circulating cerebrospinal fluid (CSF).
Cranial Meninges
These meningeal layers cover the cranium. The dura mater is the outermost layer of cranial meninges. It is a thick and durable membrane of dense...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

miR-129-3p Targeting of MCU Protects Against Glucose Fluctuation-Mediated Neuronal Damage via a Mitochondrial-Dependent Intrinsic Apoptotic Pathway.

Diabetes, metabolic syndrome and obesity : targets and therapy·2021
Same author

Malignancy Risk Stratification Prediction of Amorphous Calcifications Based on Clinical and Mammographic Features.

Cancer management and research·2021
Same author

Comparison of clinical and histopathological characteristics of short-term progressive and non-progressive blood blister-like aneurysms.

Acta neurochirurgica·2021
Same author

Duration and choices of prophylactic anticonvulsants in subarachnoid hemorrhage: a systematic review and meta-analysis.

Neurosurgical review·2021
Same author

Changes in Characteristics, Treatment and Outcome in Patients with Hemorrhagic Stroke During COVID-19.

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association·2020
Same author

Mass Detection and Segmentation in Digital Breast Tomosynthesis Using 3D-Mask Region-Based Convolutional Neural Network: A Comparative Analysis.

Frontiers in molecular biosciences·2020
Same journal

Tumor control and cranial nerve outcomes after Gamma Knife radiosurgery for Glomus jugulare tumors: a systematic review, meta-analysis, and institutional failure pattern analysis.

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia·2026
Same journal

Clinical utility of maximal and minimal intensity projections in T2-weighted MRI for neurosurgical planning.

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia·2026
Same journal

Clinical and CT perfusion outcomes after direct STA-MCA bypass in moyamoya and non-moyamoya steno-occlusive disease: an Indonesian single-center cohort.

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia·2026
Same journal

Effect of non-consecutive treatment during hypofractionated stereotactic radiosurgery (HF-SRS) for brain metastases.

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia·2026
Same journal

Pre- and postoperative cranial shape analysis in Craniosynostosis: The role of mechanical loading during CT imaging.

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia·2026
Same journal

Spontaneous Recanalization of Thrombus on Ultra-High field Strength MRI.

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia·2026
See all related articles

Related Experiment Video

Updated: May 24, 2026

Label-Free Non-Linear Optics for the Study of Tubulin-Dependent Defects in Central Myelin
08:07

Label-Free Non-Linear Optics for the Study of Tubulin-Dependent Defects in Central Myelin

Published on: March 24, 2023

Central nervous system tuberculoma.

Hao Li1, Wenke Liu, Chao You

  • 1Department of Neurosurgery, West China Hospital, Sichuan University, 37 Guo Xue Xiang Road, Chengdu, Sichuan 610041, China.

Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia
|March 9, 2012
PubMed
Summary
This summary is machine-generated.

Central nervous system (CNS) tuberculoma, a benign condition, shows good prognosis with early treatment. Enhanced MRI and timely surgical decompression improve outcomes, especially for intramedullary tuberculoma.

Related Experiment Videos

Last Updated: May 24, 2026

Label-Free Non-Linear Optics for the Study of Tubulin-Dependent Defects in Central Myelin
08:07

Label-Free Non-Linear Optics for the Study of Tubulin-Dependent Defects in Central Myelin

Published on: March 24, 2023

Area of Science:

  • Neurology
  • Infectious Diseases
  • Radiology

Background:

  • Central nervous system (CNS) tuberculoma is a rare manifestation of tuberculosis.
  • Understanding its clinicoradiological features is crucial for timely diagnosis and management.

Purpose of the Study:

  • To outline the clinicoradiological features of CNS tuberculoma.
  • To emphasize the importance of early diagnosis and treatment for improved patient outcomes.

Main Methods:

  • Retrospective analysis of 23 patients diagnosed with CNS tuberculoma between 1999 and 2008.
  • Review of clinicoradiological, pathological, and follow-up data.
  • Assessment of treatment outcomes based on neurological function and Karnofsky Performance Scale scores.

Main Results:

  • The mean age of presentation was 30.3 years, with an average disease duration of six months.
  • Common locations included the thoracic (10) and intracranial (6) regions; 13% had multiple lesions.
  • Significant neurological deficits (sensory-motor and bowel/bladder involvement) were frequent; early treatment led to improved neurological function in most patients.

Conclusions:

  • CNS tuberculoma is a treatable condition with a favorable prognosis.
  • Enhanced MRI is recommended for accurate diagnosis.
  • Early surgical decompression for intramedullary tuberculoma and craniotomy for intracranial hypertension are advised; conservative management is suitable for intracranial tuberculomas without hypertension.