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Updated: May 24, 2026
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Robotic-assisted Left Pneumonectomy For Vanishing Lung Syndrome
Published on: January 23, 2026
Completion pneumonectomy: a multicentre international study on 165 patients
Giuseppe Cardillo1, Domenico Galetta, Paul van Schil
1Unit of Thoracic Surgery, Carlo Forlanini Hospital, Azienda Ospedaliera San Camillo Forlanini, Rome, Italy. gcardillo@scamilloforlanini.rm.it
Summary
Completion pneumonectomy (CP) has acceptable operative mortality but high morbidity. Survival is acceptable in selected patients, with squamous cell carcinoma showing better outcomes than adenocarcinoma. Surgical approach and neoadjuvant therapy did not impact outcomes.
Area of Science:
- Thoracic Surgery
- Surgical Oncology
- Pulmonary Medicine
Background:
- Completion pneumonectomy (CP) is a complex procedure often performed after prior lung resection.
- Factors influencing outcomes after CP require thorough investigation to optimize patient care.
Purpose of the Study:
- To evaluate factors affecting morbidity and mortality in patients undergoing completion pneumonectomy (CP).
Main Methods:
- Retrospective review of 165 consecutive patients undergoing CP across six international centers.
- Data collected included patient demographics, neoadjuvant therapy, surgical approach, and outcomes.
Main Results:
- Overall operative mortality was 10.3%, with higher rates in malignant disease (10.5%) versus benign (7.7%).
- Complications occurred in 55.1% of patients, with bronchopleural fistula in 7.9%.
- Five-year survival was 37.6% overall, with better survival for squamous cell carcinoma (48.9%) compared to adenocarcinoma (23.9%).
Conclusions:
- CP demonstrates acceptable operative mortality and high morbidity.
- Patient selection is crucial for acceptable long-term survival, particularly for squamous cell carcinoma and metastatic disease.
- Surgical approach, side of surgery, gender, and neoadjuvant therapy did not significantly influence mortality or morbidity.
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