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Updated: May 24, 2026

Laparoscopic Extracorporeal Knot-Tying for Uterine Vessel Occlusion during Hysterectomy with Cervical Cerclage in Large Uteri
Published on: September 12, 2025
Intrauterine upper extremity thrombosis successfully treated with recombinant tissue plasminogen activator,
Sadik Yurttutan1, Ramazan Ozdemir, Omer Erdeve
1Division of Neonatology, Zekai Tahir Burak Maternity Teaching Hospital, Ankara, Turkey. sdkyurttutan@gmail.com
Abstract:
Intrauterine ischemia of the limbs is a rare condition involving thrombosis and ischemia of the extremities before birth. The clinical presentation depends on the extremity affected as well as the timing of thrombosis. Very few cases with extremity hypoperfusion and gangrene due to intrauterine thrombosis have been reported in the literature, and therefore there is no consensus on the optimal therapeutic strategy for such cases. Presented here is a case of a newborn with intrauterine brachial arterial thrombosis of the right upper extremity who was successfully treated by a combination of recombinant tissue plasminogen activator, enoxaparin and collagenase application followed by surgery.
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