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Updated: May 24, 2026
06:45
Colon Ascendens Stent Peritonitis (CASP) - a Standardized Model for Polymicrobial Abdominal Sepsis
Published on: December 18, 2010
[Spontaneous bacterial peritonitis].
S A Schmid1, R Wiest, B Salzberger
1Klinik und Poliklinik für Innere Medizin I, Universitätsklinikum Regensburg, Franz-Josef-Strauß-Allee 11, Regensburg, Germany. stephan.schmid@ukr.de
Medizinische Klinik, Intensivmedizin Und Notfallmedizin
|March 9, 2012
Summary
Spontaneous bacterial peritonitis (SBP) is a common infection in cirrhosis patients, leading to high mortality. Prompt diagnosis via ascitic fluid analysis and immediate antibiotic treatment are crucial for managing SBP.
Area of Science:
- Gastroenterology and Hepatology
- Infectious Diseases
Context:
- Spontaneous bacterial peritonitis (SBP) is the most common infection in hospitalized cirrhosis patients.
- SBP is linked to significant acute and long-term mortality.
- Diagnosis relies on ascitic fluid analysis, specifically neutrophil count.
Purpose:
- To outline the diagnostic and therapeutic strategies for spontaneous bacterial peritonitis (SBP).
- To emphasize the importance of timely intervention and appropriate antibiotic selection.
- To discuss prophylaxis and the emerging issue of antibiotic resistance.
Summary:
- SBP diagnosis involves paracentesis and neutrophil count in ascitic fluid.
- Immediate empirical antibiotic therapy is essential, guided by previous treatments.
- Liver transplantation is an option for eligible patients.
- Prophylaxis is recommended for specific patient groups, including those with ascites, GI hemorrhage, or a history of SBP.
- Primary prophylaxis may be considered for high-risk cirrhosis patients with ascites.
Impact:
- Highlights the critical need for prompt SBP diagnosis and treatment to reduce mortality.
- Informs clinical decision-making regarding antibiotic choice and prophylaxis strategies.
- Raises awareness of antibiotic resistance as a significant concern in SBP management.
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