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The association between change in cognitive function and longevity in Dutch elderly.

D J Deeg1, A Hofman, R J van Zonneveld

  • 1Department of Public Health and Social Medicine, Erasmus University Medical School, Rotterdam, The Netherlands.

American Journal of Epidemiology
|November 1, 1990
PubMed
Summary

Cognitive decline predicts longevity in older adults. A study found that a faster rate of cognitive function decline was linked to shorter survival times in individuals aged 70 and over.

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Area of Science:

  • Gerontology
  • Cognitive Neuroscience
  • Epidemiology

Background:

  • Cognitive function naturally declines with age.
  • Understanding predictors of longevity is crucial for public health.
  • Previous research has explored cognitive function and mortality, but the rate of change is less understood.

Purpose of the Study:

  • To investigate the association between the rate of change in cognitive function and longevity.
  • To determine if cognitive decline predicts survival time in older adults.

Main Methods:

  • Utilized data from the Dutch Longitudinal Study Among the Elderly.
  • Followed 211 individuals aged 65-84 for 8 years, assessing cognitive function twice using an adaptation of the Wechsler Memory Scale.
  • Determined the rate of cognitive change via regression analysis and ascertained mortality through 1983.

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Main Results:

  • Cognitive function significantly declined over the 8-year follow-up period (mean yearly change: -0.28 units).
  • A faster rate of cognitive decline was strongly associated with shorter subsequent survival time in individuals aged 70 and over.
  • This association remained significant after adjusting for potential confounders and was not observed in the 65-69 age group.

Conclusions:

  • The rate of cognitive function decline is an independent predictor of longevity in older individuals (aged 70+).
  • Monitoring cognitive change may offer insights into future survival.
  • These findings highlight the importance of cognitive health in aging research.