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Updated: Oct 1, 2026

Establishment of a Human Multiple Myeloma Xenograft Model in the Chicken to Study Tumor Growth, Invasion and Angiogenesis
Published on: May 1, 2015
Necrobiotic xanthogranuloma with IgA multiple myeloma: a case report and literature review
E A Valentine1, H D Friedman, K W Zamkoff
1Department of Medicine, Veterans Administration Hospital, Syracuse, New York.
Abstract:
The association between necrobiotic xanthogranuloma of the dermis and paraproteinemia and/or B-cell malignancy is best described in the ophthalmologic literature. We report a case which occurred in the eyelid and orbit of a 64 year old man that led to the diagnosis of an IgA multiple myeloma. To our knowledge, this is the first report of an IgA type paraproteinemia and IgA type multiple myeloma associated with necrobiotic xanthogranuloma.
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