Related Experiment Video
Updated: May 24, 2026
Single-Port Robotic-assisted Transaxillary Breast-conserving Surgery: A Prospective, Single-arm, Non-randomized Phase IIa Clinical Trial
Published on: August 19, 2025
Intraoperative ultrasound: improved resection rates in breast-conserving surgery
Christian Eichler1, Annette Hübbel, Verena Zarghooni
1Department of Senology, University of Cologne, Germany. ceichler@gmail.com
Aim:
The objective of this study was the investigation of a possible improvement of tumor resection rate, i.e. R0 vs. R1 resection when intraoperative ultrasound evaluation of tissue margins is used during breast-conserving surgery (BCS).
Patients And Methods:
A total of 250 cases were evaluated retrospectively. The impact of ultrasound analysis onto clean margin rates was evaluated. A subgroup analysis assessed histology, stage, and neoadjuvant therapy with respect to R0 resection rate and ultrasound evaluation.
Results:
Of 250 BCS cases 84, (33.6%) underwent intraoperative ultrasound and 166 (66.4%) did not. Clean primary surgical margins (R0) were demonstrated for 218 (87.2%) patients after histological analysis. R0 resection was achieved in 81 (96.4%) patients in the ultrasound group compared to 137 (82.5%) in the control group. The difference between the two groups is significant.
Conclusion:
This study revealed a significant increase in R0 resection rates when intraoperative ultrasound was used to evaluate surgical margins.
