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Updated: May 24, 2026

Employing Pressurized Hot Water Extraction (PHWE) to Explore Natural Products Chemistry in the Undergraduate Laboratory
Published on: November 7, 2018
[Laboratories "Produits Scientia" and mineral waters from Pougues and Carabana]
Cécile Raynal1, Thierry Lefebvre
1Univ Paris Diderot, Sorbonne Paris Cité, Cerilac, 75205 Paris.
Abstract:
In the end of XIXth century, the french "Compagnie des eaux minérales de Pougues-les-Eaux" begins to exploit the spanish natural purgativ water of Carabaña. In the same way, Edouard Jéramec, director of the french compagny, decides to associate to his firm the best medicine to fight against rickets and tuberculosis. He joins the new medical theory wich recommends to give more calcium to tubercular patients, called "méthode de recalcification du Dr Ferrier". Then, with the chemist Emile Perraudin, he creates the pharmaceutical laboratory named "Produits Scientia". One of their famous patents medicines will be the "Tricalcine".

