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Related Concept Videos

Allergic Reactions: Anaphylaxis01:30

Allergic Reactions: Anaphylaxis

Anaphylaxis is a severe, life-threatening hypersensitivity reaction mediated by Immunoglobulin E (IgE) antibodies. When IgE binds to allergens, it triggers the release of mediators– histamine, leukotrienes, and prostaglandins from mast cells and basophils. These mediators cause vasodilation, edema, and inflammation, leading to various symptoms.The primary allergens causing anaphylaxis include food items (e.g., peanuts, shellfish), drugs (e.g., penicillin, asparaginase, corticotropin, heparin),...
Treatment for Pulmonary Arterial Hypertension: Oxygen Therapy for Respiratory Failure01:16

Treatment for Pulmonary Arterial Hypertension: Oxygen Therapy for Respiratory Failure

Oxygen therapy has emerged as a significant tool in enhancing the quality of life for patients suffering from pulmonary arterial hypertension (PAH). While this therapy has principally been studied on patients with significant hypoxemia, this therapeutic approach helps prevent potential organ damage and can be administered in the comfort of one's home.
Oxygen therapy is vital in increasing and maintaining blood oxygen levels in PAH patients. As a result, it aids in reducing fatigue, improving...
Hyperpnea and Hyperventilation01:25

Hyperpnea and Hyperventilation

Hyperventilation refers to a higher-than-normal rate and depth of breathing, often associated with anxiety attacks. This excessive breathing surpasses the body's need to expel CO2, leading to a condition known as hypocapnia - an unusually low level of carbon dioxide in the blood. Hypocapnia can constrict cerebral blood vessels, reducing blood flow to the brain, which may result in dizziness or fainting. Early signs include tingling and muscle spasms in the hands and face, caused by falling...
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Overview
Pneumothorax-I01:26

Pneumothorax-I

A pneumothorax is a condition where air builds up in the space between the lung and the chest wall, causing the lung to collapse. This condition arises when air enters the space between the parietal and visceral pleura, disrupting the negative pressure essential for lung inflation. This can lead to a partial or complete collapse of the lung.
Pneumothorax can be even further classified as spontaneous, traumatic, and tension pneumothorax.
Hypoxia01:23

Hypoxia

Hypoxia is a medical condition characterized by an inadequate oxygen supply to body tissues. It typically manifests as a bluish discoloration of the skin and mucosae, especially in fair-skinned individuals, when hemoglobin (Hb) saturation drops below 75%.
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There are four primary types of hypoxia, each resulting from a different cause:
1. Anemic hypoxia: This type occurs due to insufficient oxygen delivery caused by a lack of red blood cells (RBCs) or RBCs with abnormal or...

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Anaphylactic shock during hyperbaric oxygen therapy.

M Marmo1, C Sacerdoti, R M Di Minno

  • 1Department of Anesthesiology and Intensive Care, H.B.O.T. Unit, Antonio Cardarelli Hospital, Naples, Italy. dott.marianomarmo@live.it

Undersea & Hyperbaric Medicine : Journal of the Undersea and Hyperbaric Medical Society, Inc
|March 10, 2012
PubMed
Summary
This summary is machine-generated.

A patient experienced a severe latex-induced anaphylactic reaction during hyperbaric oxygen therapy. This case highlights the critical need for latex-safe protocols in hyperbaric environments.

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Area of Science:

  • Allergy and Immunology
  • Hyperbaric Medicine
  • Emergency Medicine

Background:

  • Hyperbaric oxygen therapy (HBOT) is a treatment involving breathing pure oxygen in a pressurized chamber.
  • Patients undergoing HBOT may have pre-existing conditions, including allergies, that require careful consideration.
  • Latex allergy is a growing concern, with potential for severe reactions in various medical settings.

Observation:

  • A 38-year-old woman with a history of oral-allergy syndrome and latex sensitivity developed anaphylaxis during HBOT.
  • Symptoms included malaise, anxiety, dyspnea, tachycardia, cold sweating, and laryngeal stridor, commencing 15 minutes into compression.
  • Facial angioedema persisted for several days despite intensive care management.

Findings:

  • Diagnostic tests, including radioallergosorbent test (RAST) and prick tests, implicated latex as the cause of the anaphylactic reaction.
  • This is reportedly the first extensive case report of a latex-induced anaphylactic reaction within a hyperbaric chamber.
  • The patient's pre-existing sensitivities to certain fruits (oral-allergy syndrome) and latex were key historical factors.

Implications:

  • Healthcare providers must conduct thorough patient histories to identify potential allergens before HBOT.
  • The establishment of latex-safe hyperbaric chambers is crucial for managing patients with latex allergies.
  • Maintaining readily accessible emergency kits is essential for managing severe allergic reactions during HBOT.