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Updated: May 24, 2026

Collecting Saliva and Measuring Salivary Cortisol and Alpha-amylase in Frail Community Residing Older Adults via Family Caregivers
Published on: December 18, 2013
Focus on methodology: salivary bioscience and research on adolescence: an integrated perspective
Douglas A Granger1, Christine K Fortunato, Emilie K Beltzer
1Center for Interdisciplinary Salivary Bioscience Research, Johns Hopkins University, Baltimore, MD 21205-2110, USA. dgrange2@jhu.edu
Abstract:
The characterization of the salivary proteome and advances in biotechnology create an opportunity for developmental scientists to measure multi-level components of biological systems in oral fluids and identify relationships with developmental processes and behavioral and social forces. The implications for developmental science are profound because from a single oral fluid specimen, information can be obtained about a broad array of biological systems and the genetic polymorphisms related to their function. The purpose of this review is to provide a conceptual and tactical roadmap for investigators interested in integrating these measurement tools into research on adolescent health and development.
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