Related Experiment Video
Updated: May 24, 2026

Bilayer Microfluidic Device for Combinatorial Plug Production
Published on: December 1, 2023
Experimental validation of plugging during drop formation in a T-junction
Adam R Abate1, Pascaline Mary, Volkert van Steijn
1School of Engineering and Applied Sciences and Department of Physics, Harvard University, Cambridge, Massachusetts, USA. adam.abate@ucsf.edu
Abstract:
At low capillary number, drop formation in a T-junction is dominated by interfacial effects: as the dispersed fluid flows into the drop maker nozzle, it blocks the path of the continuous fluid; this leads to a pressure rise in the continuous fluid that, in turn, squeezes on the dispersed fluid, inducing pinch-off of a drop. While the resulting drop volume predicted by this "squeezing" mechanism has been validated for a range of systems, as of yet, the pressure rise responsible for the actual pinch-off has not been observed experimentally. This is due to the challenge of measuring the pressures in a T-junction with the requisite speed, accuracy, and localization. Here, we present an empirical study of the pressures in a T-junction during drop formation. Using Laplace sensors, pressure probes we have developed, we confirm the central ideas of the squeezing mechanism; however, we also uncover other findings, including that the pressure of the dispersed fluid is not constant but rather oscillates in anti-phase with that of the continuous fluid. In addition, even at the highest capillary number for which monodisperse drops can be formed, pressure oscillations persist, indicating that drop formation in confined geometries does not transition to an entirely shear-driven mechanism, but to a mechanism combining squeezing and shearing.
Related Concept Videos
Formation of the Platelet Plug
As the injured blood vessel contracts, endothelial cells undergo contraction, revealing collagen fibers in the basement membrane and underlying connective tissue. Furthermore, the plasma membrane of endothelial cells becomes adhesive, preparing the site for platelet adhesion. Platelets...
Steady, Laminar Flow Between Parallel Plates
The Joule and Joule–Thomson Experiments
Theories of Dissolution: The Danckwerts' Model and Interfacial Barrier Model
P-N junction

